Nrf2 is a master transcription factor that regulates a wide variety of cellular proteins by
recognizing and binding to antioxidant response elements (AREs) in their gene promoter …

Cells are equipped with a number of transcriptional factors that safeguard against various
environmental insults. Proteasomal protein degradation plays an important role in the Keap1 …

Nrf2 is the key transcription factor regulating the antioxidant response. When exposed to
oxidative stress, Nrf2 translocates to cell nucleus and forms heterodimer with small Maf …

Nrf2 is a key transcription factor in the cellular response to oxidative stress. In this study we
identify two phosphorylated forms of endogenous human Nrf2 after chemically induced …

Oxidative stress plays an important part in the pathogenesis of a variety of diseases. The
ability to mount an efficient response against the continuous threat posed by exogenous and …

The antioxidant responsive element (ARE) is a cis-acting regulatory element of genes
encoding phase II detoxification enzymes and antioxidant proteins, such as NAD (P) H …

The transcription factor Nrf2 regulates the basal and inducible expression of numerous
detoxifying and antioxidant genes. The cytoplasmic protein Keap1 interacts with Nrf2 and …

Nrf2 (NF-E2-related factor 2) is a nuclear transcription factor that in response to chemical
and radiation stress regulates coordinated induction of a battery of cytoprotective gene …

The Nrf2 transcription factor is more rapidly turned over in cells grown under homeostatic
conditions than in those experiencing oxidative stress. The variable turnover of Nrf2 is …

Abstract Nuclear Factor Erythroid 2-related factor 2 (Nrf2) is a transcription factor that
regulates the expression of genes involved in the metabolism, immune response, cellular …