Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

Stem cells and other functionally defined therapeutic cells (eg, T cells) are promising to bring
hope of a permanent cure for diseases and disorders that currently cannot be cured by …

Conspectus Cell therapy has become a momentum-gathering treatment strategy for a variety
of diseases, including cancer, diabetes, hemophilia, and cardiomyopathy. However, clinical …

Synthetic biology seeks to redesign biological systems to perform novel functions in a
predictable manner. Recent advances in bacterial and mammalian cell engineering include …

Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …

The next generation of therapeutic products to be approved for the clinic is anticipated to be
cell therapies, termed “living drugs” for their capacity to dynamically and temporally respond …

The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …

Two decades ago, the pharmaceutical industry—long dominated by small-molecule drugs—
was revolutionized by the the advent of biologics. Today, biomedicine sits on the cusp of a …

The field of Metabolic Engineering has recently undergone a transformation that has led to a
rapid expansion of the chemical palate of cells. Now, it is conceivable to produce nearly any …