Determinants of the proinflammatory action of ambient particulate matter in immortalized murine macrophages

C Guastadisegni, FJ Kelly, FR Cassee… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Proximity to traffic-related pollution has been associated with poor respiratory
health in adults and children. Objectives We wished to test the hypothesis that particulate …

Particulate matter from Saudi Arabia induces genes involved in inflammation, metabolic syndrome and atherosclerosis

J Brocato, H Sun, M Shamy, T Kluz… - Journal of Toxicology …, 2014 - Taylor & Francis
Airborne particulate matter (PM) exposure is a major environmental health concern and is
linked to metabolic disorders, such as cardiovascular diseases (CVD) and diabetes, which …

Long-term exposure to PM2. 5 lowers influenza virus resistance via down-regulating pulmonary macrophage Kdm6a and mediates histones modification in IL-6 and …

JH Ma, SH Song, M Guo, J Zhou, F Liu, L Peng… - Biochemical and …, 2017 - Elsevier
Abstract Atmospheric particulates, especially PM2. 5, not only damage the respiratory
system, but also play important roles in pulmonary immunity. China is influenced by …

[HTML][HTML] PM2. 5 exposure in the respiratory system induces distinct inflammatory signaling in the lung and the liver of mice

S Jeong, SA Park, I Park, P Kim, NH Cho… - Journal of immunology …, 2019 - hindawi.com
Fine particulate matter 2.5 (PM2. 5) is a harmful air pollutant currently threatening public
health. Although many studies have been performed on the general negative effects of PM2 …

TH17-Induced Neutrophils Enhance the Pulmonary Allergic Response Following BALB/c Exposure to House Dust Mite Allergen and Fine Particulate Matter From …

J Zhang, CC Fulgar, T Mar, DE Young… - Toxicological …, 2018 - academic.oup.com
Asthma is a global and increasingly prevalent disease. According to the World Health
Organization, approximately 235 million people suffer from asthma. Studies suggest that fine …

[HTML][HTML] In-vitro human lung cell injuries induced by urban PM2. 5 during a severe air pollution episode: variations associated with particle components

Y Pang, W Huang, XS Luo, Q Chen, Z Zhao… - Ecotoxicology and …, 2020 - Elsevier
Environmental air pollutants pose significant threats to public health, especially the toxicity
and diseases caused by the atmospheric fine particulate matters (PM 2.5). Since the health …

[HTML][HTML] Fine particulate matter 2.5 exerted its toxicological effect by regulating a new layer, long non-coding RNA

Q Huang, Y Chi, J Deng, Y Liu, Y Lu, J Chen, S Dong - Scientific reports, 2017 - nature.com
Abstract Fine particulate matter (PM2. 5) exposure, especially to its organic components,
induces adverse health effects on the respiratory system. However, the molecular …

Associations of exposure to fine particulate matter mass and constituents with systemic inflammation: a cross-sectional study of urban older adults in China

B Han, J Xu, Y Zhang, P Li, K Li, N Zhang… - Environmental …, 2022 - ACS Publications
Systemic inflammation is a key mechanism in the development of cardiovascular diseases
induced by exposure to fine particles (particles with aerodynamic diameter≤ 2.5 μm [PM2 …

Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2. 5) and coarse particles (PM10–2.5) in outdoor and indoor air

C Monn, S Becker - Toxicology and applied pharmacology, 1999 - Elsevier
Increased incidence of mortality and morbidity due to cardiopulmonary complications has
been found to associate with elevated levels of particulate air pollution (particulate matter …

Repeated exposures to roadside particulate matter extracts suppresses pulmonary defense mechanisms, resulting in lipid and protein oxidative damage

M Pardo, Z Porat, A Rudich, JJ Schauer… - Environmental Pollution, 2016 - Elsevier
Exposure to particulate matter (PM) pollution in cities and urban canyons can be harmful to
the exposed population. However, the underlying mechanisms that lead to health effects are …