Ginsenoside Rg1 promotes astrocyte‐to‐neuron transdifferentiation in rat and its possible mechanism
K Shen, D Wu, B Sun, Y Zhu, H Wang… - CNS Neuroscience …, 2023 - Wiley Online Library
Introduction Neuronal loss caused by spinal cord injury (SCI) usually contributes to
irreversible motor dysfunction. Promoting neuronal regeneration and functional recovery is …
irreversible motor dysfunction. Promoting neuronal regeneration and functional recovery is …
Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling
Background and objective Tauopathy is a group of neurodegenerative diseases in which the
pathogenesis processes are related to tau protein. The imbalances between the activities of …
pathogenesis processes are related to tau protein. The imbalances between the activities of …
Neuroprotective effects of ginsenoside Rg1 through the Wnt/β-catenin signaling pathway in both in vivo and in vitro models of Parkinson's disease
T Zhou, G Zu, X Zhang, X Wang, S Li, X Gong… - …, 2016 - Elsevier
Abstract Ginsenoside Rg1 (Rg1) is a major bioactive ingredient in Panax ginseng that has
low toxicity and has been shown to have neuroprotective effects. The objectives of the …
low toxicity and has been shown to have neuroprotective effects. The objectives of the …
Gintonin, a ginseng-derived ingredient, as a novel therapeutic strategy for Huntington's disease: Activation of the Nrf2 pathway through lysophosphatidic acid …
M Jang, JH Choi, Y Chang, SJ Lee, SY Nah… - Brain, Behavior, and …, 2019 - Elsevier
Abstract Gintonin (GT), a ginseng-derived lysophosphatidic acid receptor ligand, regulates
various cellular effects and represses inflammation. However, little is known about the …
various cellular effects and represses inflammation. However, little is known about the …
Immunomodulatory and neuroprotective effects of ginsenoside Rg1 in the MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine)-induced mouse model of Parkinson's …
T Zhou, G Zu, X Wang, X Zhang, S Li, Z Liang… - International …, 2015 - Elsevier
Ginsenoside Rg1, one of the biologically active ingredients of ginseng, has been considered
to be a candidate neuroprotective drug. The objective of the study was to study the protective …
to be a candidate neuroprotective drug. The objective of the study was to study the protective …
Microglia-mediated neuroinflammation and neurotrophic factor-induced protection in the MPTP mouse model of Parkinson's disease-lessons from transgenic mice
Parkinson's disease (PD) is a neurodegenerative disease characterised by
histopathological and biochemical manifestations such as loss of midbrain dopaminergic …
histopathological and biochemical manifestations such as loss of midbrain dopaminergic …
Ginkgolide B preconditioning on astrocytes promotes neuronal survival in ischemic injury via up-regulating erythropoietin secretion
X Wu, C Zhou, F Du, Y Lu, B Peng, L Chen… - Neurochemistry …, 2013 - Elsevier
Although ischemic preconditioning (IP) can provide powerful protection on brain against
ischemic insult, it is rarely used in clinic to prevent the occurrence of ischemic stroke …
ischemic insult, it is rarely used in clinic to prevent the occurrence of ischemic stroke …
Transforming growth factor β1-mediated anti-inflammation slows progression of midbrain dopaminergic neurodegeneration in Parkinson's disease?
B Spittau - Neural regeneration research, 2015 - journals.lww.com
Parkinson's disease (PD) is characterized by the progressive loss of midbrain dopaminergic
(mDA) neurons and a subsequent decrease in striatal dopamine levels, which cause the …
(mDA) neurons and a subsequent decrease in striatal dopamine levels, which cause the …
Role of ginkgolides in the inflammatory immune response of neurological diseases: a review of current literatures
C Li, K Liu, S Liu, Q Aerqin, X Wu - Frontiers in systems neuroscience, 2020 - frontiersin.org
The inflammatory immune response (IIR) is a physiological or excessive systemic response,
induced by inflammatory immune cells according to changes in the internal and external …
induced by inflammatory immune cells according to changes in the internal and external …
[HTML][HTML] Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin …
L Liu, X Du, Q Yang, M Li, Q Ran, Q Liu, L Yang, L Sun… - Phytomedicine, 2022 - Elsevier
Background Inefficient differentiation of oligodendrocyte precursor cells (OPCs) is one of the
significant pathological obstacles of myelin repair and provides an essential therapeutic …
significant pathological obstacles of myelin repair and provides an essential therapeutic …