[HTML][HTML] Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson's disease model
J Yan, Z Yang, N Zhao, Z Li, X Cao - Bmc Neuroscience, 2019 - Springer
Background Recently, the use of traditional Chinese medicine (TCM) has become more
generally accepted, including by the Food and Drug Administration. To expand the use of …
generally accepted, including by the Food and Drug Administration. To expand the use of …
Galectin-1 attenuates neurodegeneration in Parkinson's disease model by modulating microglial MAPK/IκB/NFκB axis through its carbohydrate-recognition domain
Y Li, N Chen, C Wu, Y Lu, G Gao, C Duan… - Brain, Behavior, and …, 2020 - Elsevier
The vicious cycle between the chronic activation of microglia and dopamine neurons
degeneration is linked with the progression of Parkinson's disease (PD). Targeting …
degeneration is linked with the progression of Parkinson's disease (PD). Targeting …
[HTML][HTML] Galangin reduces the loss of dopaminergic neurons in an LPS-evoked model of Parkinson's disease in rats
G Chen, J Liu, L Jiang, X Ran, D He, Y Li… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is caused by the loss of dopaminergic (DA) neurons in the
midbrain substantia nigra (SN). Neuroinflammation, which is marked by microglial activation …
midbrain substantia nigra (SN). Neuroinflammation, which is marked by microglial activation …
Protection of MPTP-induced neuroinflammation and neurodegeneration by rotigotine-loaded microspheres
X Yu, JY Yao, J He, JW Tian - Life sciences, 2015 - Elsevier
Aims The aim of the study is to evaluate the neuroprotective effects of continuous
dopaminergic stimulation (CDS) by rotigotine-loaded microspheres (RoMS) in a mouse …
dopaminergic stimulation (CDS) by rotigotine-loaded microspheres (RoMS) in a mouse …
Echinacoside protects dopaminergic neurons by inhibiting NLRP3/Caspase-1/IL-1β signaling pathway in MPTP-induced Parkinson's disease model
MR Gao, M Wang, YY Jia, DD Tian, A Liu, WJ Wang… - Brain research …, 2020 - Elsevier
Persistent microglia-mediated neuroinflammation contributes to the progressive loss of
dopaminergic (DA) neurons in Parkinson's disease (PD). Recently, NOD-like receptor …
dopaminergic (DA) neurons in Parkinson's disease (PD). Recently, NOD-like receptor …
FTY720 Inhibits MPP+-Induced Microglial Activation by Affecting NLRP3 Inflammasome Activation
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons
and excessive microglial activation in the substantia nigra pars compacta (SNpc). In the …
and excessive microglial activation in the substantia nigra pars compacta (SNpc). In the …
[HTML][HTML] Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways
X Zhang, M Shi, M Bjørås, W Wang, G Zhang… - Frontiers in …, 2013 - frontiersin.org
Ginsenoside Rd (Rd), one of the main active ingredients in Panax ginseng, has been
showed to protect against ischemic cerebral damage both in vitro and in vivo. However, the …
showed to protect against ischemic cerebral damage both in vitro and in vivo. However, the …
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia
H Xiao, Q Jiang, H Qiu, K Wu, X Ma, J Yang… - Neurochemistry …, 2021 - Elsevier
Gastrodin, which is extracted from the Chinese herbal medicine Gastrodia elata Blume, can
ameliorate neurogenesis after cerebral ischemia. However, it's possible underlying …
ameliorate neurogenesis after cerebral ischemia. However, it's possible underlying …
Korean red ginseng and ginsenoside-Rb1/-Rg1 alleviate experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells and upregulating …
MJ Lee, M Jang, J Choi, BS Chang, DY Kim… - Molecular …, 2016 - Springer
The effects of Korean red ginseng extract (KRGE) on autoimmune disorders of the nervous
system are not clear. We investigated whether KRGE has a beneficial effect on acute and …
system are not clear. We investigated whether KRGE has a beneficial effect on acute and …
Synthesis, biological activity evaluation and mechanism analysis of new ganglioside GM3 derivatives as potential agents for nervous functional recovery
Y Lin, J Wang, X Liu, Y Hu, Y Zhang, F Jiang - European Journal of …, 2024 - Elsevier
Neuronal regenerative ability is vital for the treatment of neurodegenerative diseases and
neuronal injuries. Recent studies have revealed that Ganglioside GM3 and its derivatives …
neuronal injuries. Recent studies have revealed that Ganglioside GM3 and its derivatives …