PURPOSE Therapeutic radiation in childhood cancer has decreased over time with a
concomitant increase in chemotherapy. Limited data exist on chemotherapy-associated …

Subsequent malignant neoplasms (SMNs) in childhood cancer survivors cause substantial
morbidity and mortality. This review summarizes recent literature on SMN epidemiology, risk …

Purpose Childhood cancer survivors (CCSs) are at increased risk for subsequent malignant
neoplasms (SMNs). We evaluated the long-term risk of SMNs in a well-characterized cohort …

Purpose To review the reports of subsequent neoplasms (SNs) in the Childhood Cancer
Survivor Study (CCSS) cohort that were made through January 1, 2006, and published …

PURPOSE Chemotherapeutic exposures are associated with subsequent malignant
neoplasm (SMN) risk. The role of genetic susceptibility in chemotherapy-related SMNs …

Background: Because survival rates among childhood cancer patients are increasing,
assessing the risk of second and subsequent malignant neoplasms (SMNs) is ever more …

Purpose Survivors of childhood cancer have an increased risk for subsequent neoplasms
(SNs), but the incidence beyond the age of 40 years and associations with therapeutic …

Purpose To determine the risk of subsequent carcinomas other than breast, thyroid, and
skin, and to identify factors that influence the risk among survivors of childhood cancer …

Importance Cancer treatments are associated with subsequent neoplasms in survivors of
childhood cancer. It is unknown whether temporal changes in therapy are associated with …

PURPOSE: Childhood cancer survivors have an increased risk of secondary sarcomas. To
better identify those at risk, the relationship between therapeutic dose of chemotherapy and …