Members of the regulatory lymphocyte club in common variable immunodeficiency

S Gupta, Y Demirdag, AA Gupta - Frontiers in Immunology, 2022 - frontiersin.org
The role of CD4 T regulatory cells is well established in peripheral tolerance and the
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …

[HTML][HTML] Updates on the pathogenesis of common variable immunodeficiency (CVID)

T Martelius, MRJ Seppänen, K Warnatz - Frontiers in Immunology, 2023 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common clinically manifest inborn
error of immunity. Definitions of CVID have evolved over years. Infections or autoimmunity …

Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

J Rodríguez-Ubreva, A Arutyunyan, MJ Bonder… - Nature …, 2022 - nature.com
Common variable immunodeficiency (CVID), the most prevalent symptomatic primary
immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody …

Current understanding and recent developments in common variable immunodeficiency associated autoimmunity

JD Gereige, PJ Maglione - Frontiers in immunology, 2019 - frontiersin.org
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary
immunodeficiency and comprises a group of disorders with similar antibody deficiency but a …

The immune dysregulation of common variable immunodeficiency disorders

SL Fernando, HSI Jang, J Li - Immunology Letters, 2021 - Elsevier
Common variable immunodeficiency (CVID) is established as a heterogeneous collection of
disorders of immune dysregulation rather than an infectious complication of antibody …

Unravelling the complexity of T cell abnormalities in common variable immunodeficiency

A Giovannetti, M Pierdominici, F Mazzetta… - The Journal of …, 2007 - journals.aai.org
We investigated several phenotypic and functional parameters of T cell-mediated immunity
in a large series of common variable immunodeficiency (CVID) patients. We demonstrated …

Monogenic forms of common variable immunodeficiency and implications on target therapeutic approaches

G Tessarin, M Baronio, V Lougaris - Current Opinion in Allergy and …, 2023 - journals.lww.com
Monogenic forms of common variable immunodeficiency and impl... : Current Opinion in Allergy
and Clinical Immunology Monogenic forms of common variable immunodeficiency and …

Seeking relevant biomarkers in common variable immunodeficiency

H Ho, C Cunningham-Rundles - Frontiers in Immunology, 2022 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic form of
primary immunodeficiency. More than 50% of patients in some series suffer from …

[HTML][HTML] Common variable immunodeficiency (CVID): new genetic insight and unanswered questions

HD Ochs - Clinical and Experimental Immunology, 2014 - ncbi.nlm.nih.gov
Common variable immunodeficiency (CVID) is a clinically and molecularly heterogeneous
disorder with a varied clinical presentation [1]. The age of onset varies from early childhood …

Common variable immunodeficiency is associated with defective functions of dendritic cells

J Bayry, S Lacroix-Desmazes, MD Kazatchkine… - Blood, 2004 - ashpublications.org
Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia
and defects in T-cell functions that could be primary or secondary. We addressed whether …