During axial loading or non-physiologic motions of the neck, the cervical nerve roots can
become transiently compressed by the surrounding bony structures of the intervertebral …

Cervical nerve root injury commonly leads to pain. The duration of an applied compression
has been shown to contribute to both the onset of persistent pain and also the degree of …

As many as 30% of Americans suffer from chronic pain. Both chemical irritation and
mechanical compression have been implicated in nerve root-mediated pain. However, the …

Study Design. An in vivo rat model of transient cervical nerve root compression. Objectives.
To investigate the potential for cervical nerve root compression to produce behavioral …

Nerve root compression produces chronic pain and altered spinal neuropeptide expression.
This study utilized controlled transient loading in a rat model of painful cervical nerve root …

Rapid neck motions can load cervical nerve roots and produce persistent pain. This study
investigated the cellular basis of radicular pain and mechanical implications of tissue …

Nerve root compression produces persistent behavioral sensitivity in models of painful neck
injury. This study utilized degradable poly (ethylene glycol) hydrogels to deliver glial cell line …

BACKGROUND CONTEXT: Spinal nerve roots have been identified as sources of low back
pain. While risk of such injury exists in the cervical spine due to neck motions, no study has …

Study Design. Behavioral and immunohistochemical analysis in rat models of persistent and
transient allodynia. Objectives. To examine separate cervical nerve root injuries …

Both traumatic and slow-onset disc herniation can directly compress and/or chemically
irritate cervical nerve roots, and both types of root injury elicit pain in animal models of …