[HTML][HTML] Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos… - Cell stem cell, 2021 - cell.com
Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …
development, disease, and regeneration. As organoid research expands, the need for clear …
Next-generation liver medicine using organoid models
“Liver medicine” refers to all diagnostic and treatment strategies of diseases and conditions
that cause liver failure directly or indirectly. Despite significant advances in the field of liver …
that cause liver failure directly or indirectly. Despite significant advances in the field of liver …
Organoids and regenerative hepatology
N Jalan‐Sakrikar, T Brevini, RC Huebert… - Hepatology, 2023 - journals.lww.com
The burden of liver diseases is increasing worldwide, with liver transplantation remaining
the only treatment option for end‐stage liver disease. Regenerative medicine holds great …
the only treatment option for end‐stage liver disease. Regenerative medicine holds great …
Concise review: organoids are a powerful tool for the study of liver disease and personalized treatment design in humans and animals
S Nantasanti, A de Bruin, J Rothuizen… - Stem cells …, 2016 - academic.oup.com
Organoids are three-dimensional culture systems in which adult stem cells and their
progeny grow and represent the native physiology of the cells in vivo. Organoids have been …
progeny grow and represent the native physiology of the cells in vivo. Organoids have been …
Hepatobiliary organoids and their applications for studies of liver health and disease: are we there yet?
Organoid culture systems have emerged as a frontier technology in liver and biliary
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …
Liver organoids: from basic research to therapeutic applications
Organoid cultures have emerged as an alternative in vitro system to recapitulate tissues in a
dish. While mouse models and cell lines have furthered our understanding of liver biology …
dish. While mouse models and cell lines have furthered our understanding of liver biology …
[HTML][HTML] Organoids to model liver disease
S Nuciforo, MH Heim - JHEP Reports, 2021 - Elsevier
The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
Liver organoids: recent developments, limitations and potential
SP Harrison, SF Baumgarten, R Verma, O Lunov… - Frontiers in …, 2021 - frontiersin.org
Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to
investigate development, toxicity, as well as genetic and infectious disease in ways currently …
investigate development, toxicity, as well as genetic and infectious disease in ways currently …
Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids
SJ Mun, JS Ryu, MO Lee, YS Son, SJ Oh, HS Cho… - Journal of …, 2019 - Elsevier
Background & Aims The development of hepatic models capable of long-term expansion
with competent liver functionality is technically challenging in a personalized setting. Stem …
with competent liver functionality is technically challenging in a personalized setting. Stem …
Progress in human liver organoids
L Sun, L Hui - Journal of Molecular Cell Biology, 2020 - academic.oup.com
Understanding the development, regeneration, and disorders of the liver is the major goal in
liver biology. Current mechanistic knowledge of human livers has been largely derived from …
liver biology. Current mechanistic knowledge of human livers has been largely derived from …