The use of stem cell-derived organoids in disease modeling: an update

J Azar, HF Bahmad, D Daher, MM Moubarak… - International Journal of …, 2021 - mdpi.com
Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …

Human organoids share structural and genetic features with primary pancreatic adenocarcinoma tumors

I Romero-Calvo, CR Weber, M Ray, M Brown… - Molecular Cancer …, 2019 - AACR
Patient-derived pancreatic ductal adenocarcinoma (PDAC) organoid systems show great
promise for understanding the biological underpinnings of disease and advancing …

Concise review: the relevance of human stem cell-derived organoid models for epithelial translational medicine

RE Hynds, A Giangreco - Stem cells, 2013 - academic.oup.com
Epithelial organ remodeling is a major contributing factor to worldwide death and disease,
costing healthcare systems billions of dollars every year. Despite this, most fundamental …