Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …

Characterized by multiple complex mutations, including activation by oncogenes and
inhibition by tumor suppressors, cancer is one of the leading causes of death. Application of …

Clustered regularly interspaced short palindromic repeats/CRISPR‐associated nuclease 9
(CRISPR‐Cas9) is an RNA‐guided gene editing tool which offers several advantageous …

In recent years, gene editing, especially that using clustered regularly interspaced short
palindromic repeat (CRISPR)/Cas9, has made great progress in the field of gene function …

Cancer is one of the most leading causes of death and a major public health problem,
universally. According to accumulated data, annually, approximately 8.5 million people died …

The development of genetic engineering in the 1970s marked a new frontier in genome-
editing technology. Gene-editing technologies have provided a plethora of benefits to the life …

At present, the idea of genome modification has revolutionized the modern therapeutic
research era. Genome modification studies have traveled a long way from gene …

The CRISPR system is a revolutionary genome editing tool that has the potential to
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …

Clustered regularly interspaced short palindromic repeats (CRISPR) system provides
adaptive immunity against plasmids and phages in prokaryotes. This system inspires the …

Cancer is characterized by multiple genetic and epigenetic alterations that drive malignant
cell proliferation and confer chemoresistance. The ability to correct or ablate such mutations …