Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine
Vaccination can provide a safe alternative to chemotherapy by using the body's natural
defense mechanisms to create a potent immune response against tumor cells. Peptide …
defense mechanisms to create a potent immune response against tumor cells. Peptide …
Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model
TY Liu, A Kumar Giddam, WM Hussein… - Current drug …, 2015 - ingentaconnect.com
Vaccine candidates for the treatment of human papillomavirus (HPV)-associated cancers
are aimed to activate T-cells and induce development of cytotoxic anti-tumor specific …
are aimed to activate T-cells and induce development of cytotoxic anti-tumor specific …
Self-assembling peptide epitopes as novel platform for anticancer vaccination
M Rad-Malekshahi, MF Fransen… - Molecular …, 2017 - ACS Publications
The aim of the present study was to improve the immunogenicity of peptide epitope vaccines
using novel nanocarriers based on self-assembling materials. Several studies demonstrated …
using novel nanocarriers based on self-assembling materials. Several studies demonstrated …
Multiantigenic peptide–polymer conjugates as therapeutic vaccines against cervical cancer
Immunotherapy is one of the most promising strategies for the treatment of cancer. Human
papillomavirus (HPV) is responsible for virtually all cases of cervical cancer. The main …
papillomavirus (HPV) is responsible for virtually all cases of cervical cancer. The main …
Multifunctional protein conjugates with built-in adjuvant (adjuvant-protein-antigen) as cancer vaccines boost potent immune responses
JJ Du, CW Wang, WB Xu, L Zhang, YK Tang, SH Zhou… - Iscience, 2020 - cell.com
Many cancer vaccines are not successful in clinical trials, mainly due to the challenges
associated with breaking immune tolerance. Herein, we report a new strategy using an …
associated with breaking immune tolerance. Herein, we report a new strategy using an …
Improving the efficacy of peptide vaccines in cancer immunotherapy
F Zahedipour, K Jamialahmadi, P Zamani… - International …, 2023 - Elsevier
Peptide vaccines have shown great potential in cancer immunotherapy by targeting tumor
antigens and activating the patient's immune system to mount a specific response against …
antigens and activating the patient's immune system to mount a specific response against …
[PDF][PDF] Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer
M Khongkow, TY Liu, S Bartlett… - Precision …, 2018 - precisionnanomedicine.com
Peptide-based vaccines have been proposed as a therapeutic strategy for many infectious
diseases, including human papilloma virus (HPV)-related cervical cancer. Peptide-based …
diseases, including human papilloma virus (HPV)-related cervical cancer. Peptide-based …
[HTML][HTML] Self-assembling, self-adjuvanting and fully synthetic peptide nanovaccine for cancer immunotherapy
Cancer vaccines designed to initiate or amplify tumor-specific T-cell responses have been
used as a key approach for effective cancer immunotherapy. Across the history of tumor …
used as a key approach for effective cancer immunotherapy. Across the history of tumor …
Precisely shaped self-adjuvanting peptide vaccines with enhanced immune responses for HPV-associated cancer therapy
Y Song, Q Su, H Song, X Shi, M Li, N Song… - … Applied Materials & …, 2021 - ACS Publications
Peptide vaccines exhibit great potential in cancer therapy via eliciting antigen-specific host
immune response and long-term immune memory to defend cancer cells. However, the low …
immune response and long-term immune memory to defend cancer cells. However, the low …
Synthetic, Supramolecular, and Self‐Adjuvanting CD8+ T‐Cell Epitope Vaccine Increases the Therapeutic Antitumor Immunity
P Yang, H Song, Z Feng, C Wang… - Advanced …, 2019 - Wiley Online Library
Peptide vaccines are used in clinical cancer immunotherapy, however, they generally suffer
from suboptimal immunogenicity compared to live or inactive virus vector vaccines or …
from suboptimal immunogenicity compared to live or inactive virus vector vaccines or …
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