PULMONARY changes following radiation therapy for carcinoma of the lung were
recognized as early as 1898 (2) and have been described frequently since then. Clinical …

Abnormal pulmonary changes following radiation therapy over the lungs have long been
recognized and frequently described. The object of this paper is not a description of these …

The cellular effects of irradiating the lungs are related to the histologic and clinical sequelae.
The occurrence and severity of damage are semiquantitatively related to the volume of lung …

The degenerative and fibrotic changes produced by irradiation in all tissues are of especial
significance when their presence interferes with vital functions. One of those in which this …

Although radiotherapy offers adequate palliation of symptoms in inoperable carcinoma of
the lung, the overall cure rates have been disappointing (1–4). A recent study reported a …

T HE response of the tissues of the lung to cancericidal levels of ionizing radiation forms a
complex pattern of differential damage and repair. The remarkable reserve capacity of the …

IT is well recognized that the margin between a dose of X-rays that is therapeutically
effective arid one that produces undesirable damage to adjacent healthy tissue is always …

Forty-two patients had radiotherapy to the lung for bronchogenic carcinoma. All had
pulmonary function studies before therapy and 33 had repeat studies after therapy. In 25 of …

Physiologic data concerning 30 patients with bronchogenic carcinoma were obtained before
radiation therapy and at intervals thereafter. At pretreatment examination, abnormalities …

The effects of radiotherapy on lung function, ventilation/perfusion scans, and chest
radiography were studied prospectively in 15 patients who underwent either modified …