Effects of the non-steroidal anti-inflammatory drug (NSAID) naproxen on gene expression of antioxidant enzymes in zebrafish (Danio rerio)

V Stancová, A Ziková, Z Svobodová, W Kloas - Environmental toxicology …, 2015 - Elsevier
The aim of this study was to investigate the effects of naproxen on the gene expression of
antioxidant enzymes in adult zebrafish. Surprisingly, after 2 weeks exposure no significant …

The zebrafish embryo as a model to test protective effects of food antioxidant compounds

C Arteaga, N Boix, E Teixido, F Marizande, S Cadena… - Molecules, 2021 - mdpi.com
The antioxidant activity of food compounds is one of the properties generating the most
interest, due to its health benefits and correlation with the prevention of chronic disease. This …

Identification of the Nrf2–Keap1 pathway in the European eel Anguilla anguilla: role for a transcriptional regulation of antioxidant genes in aquatic organisms

ME Giuliani, F Regoli - Aquatic Toxicology, 2014 - Elsevier
Antioxidant defences play a central role in cell protection against a wide variety of
environmental stressors, their variations being thus frequently studied to reveal oxidative …

[PDF][PDF] Evaluation of ibuprofen toxicity for zebrafish (Danio rerio) targeting on selected biomarkers of oxidative stress

M Bartoskova, R Dobsikova, V Stancova… - Neuro Endocrinol …, 2013 - academia.edu
OBJECTIVES: The aim of the study was to investigate the effects of subchronic exposure of
zebrafish to ibuprofen, using selected oxidative stress parameters as a target. DESIGN …

Modulation of antioxidant defense and immune response in zebra fish (Danio rerio) using dietary sodium propionate

R Safari, SH Hoseinifar, M Kavandi - Fish physiology and biochemistry, 2016 - Springer
The present study explores the effect of dietary sodium propionate on mucosal immune
response and expression of antioxidant enzyme genes in zebra fish (Danio rerio). Six …

Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations

C Xu, L Niu, H Guo, X Sun, L Chen, W Tu, Q Dai… - Science of the total …, 2019 - Elsevier
The presence of trace levels of pharmaceuticals is an emerging issue impacting the aquatic
ecosystem. Naproxen (NPX) is a nonsteroidal anti-inflammatory drug (NSAID) that has been …

A targeted gene expression platform allows for rapid analysis of chemical-induced antioxidant mRNA expression in zebrafish larvae

MG Mills, EP Gallagher - PloS one, 2017 - journals.plos.org
Chemical-induced oxidative stress and the biochemical pathways that protect against
oxidative damage are of particular interest in the field of toxicology. To rapidly identify …

Developmental toxicity and biological responses of zebrafish (Danio rerio) exposed to anti-inflammatory drug ketoprofen

B Rangasamy, D Hemalatha, C Shobana, B Nataraj… - Chemosphere, 2018 - Elsevier
Ketoprofen a nonsteroidal anti-inflammatory drug (NSAID) is widely used in over-the-counter
to treat pain, swelling and inflammation. Due to extensive application these drugs has been …

Transcriptional and cellular effects of paracetamol in the oyster Crassostrea gigas

MJ Bebianno, ACP Mello, MAS Serrano… - Ecotoxicology and …, 2017 - Elsevier
Abstract Acetaminophen (paracetamol)(PAR) is one of the most popular non-steroidal anti-
inflammatory drugs (NSAIDs) with analgesic and antipyretic properties consumed worldwide …

Development of an oxidative stress in vitro assay in zebrafish (Danio rerio) cell lines

S Lungu-Mitea, A Oskarsson, J Lundqvist - Scientific reports, 2018 - nature.com
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of cellular defense
against oxidative stress and correlated with classical toxicological endpoints. In vitro …