Evodiamine is a major alkaloid component found in the fruit of Evodia rutaecarpa. It shows
the anti-proliferative potential against a wide range of cancers by suppressing cell growth …

Traditional Chinese herbs are regarded as a new and promising source of potential anti-
cancer remedies and new chemotherapy adjuvants to enhance the efficacy of chemotherapy …

Evodiamine, a bioactive alkaloid, has been regarded as having antioxidant,
antiinflammatory, and anticancer properties. In the present study, we explored the effects of …

Alkaloids, a category of natural products with ring structures and nitrogen atoms, include
most US Food and Drug Administration approved plant derived anti-cancer agents …

The identification of anticancer active ingredients and their molecular targets in traditional
Chinese medicine is a great challenge in modern pharmacology research. Evodiamine is …

Evodiamine is a quinazolinocarboline alkaloid isolated from the fruits of traditional Chinese
herb Evodiae fructus. Previously, we identified N13-substituted evodiamine derivatives as …

It is a well-known phenomenon that natural products can serve as powerful drug leads to
generate new molecular entities with novel therapeutic utility. Evodiamine (Evo), a major …

Abstract Evodiae fructus (Wu‑Zhu‑Yu in Chinese) can be isolated from the dried, unripe fruits
of Tetradium ruticarpum and is a well‑known traditional Chinese medicine that is applied …

Leukemias are a heterogenous group of diseases characterized by uncontrolled
proliferation of abnormal blood cells of hematopoietic system. Evodiamine, a characteristic …

Evodiamine, an alkaloid isolated from Evodia rutaecarpa, possesses potent anticancer
activity. Although many reports have elucidated the cytotoxic effects of evodiamine in a …