Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …

R Delage, RJ Soiffer, K Dear, J Ritz - 1991 - ashpublications.org
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …

Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in …

JP Radich, G Gehly, T Gooley, E Bryant, RA Clift… - 1995 - ashpublications.org
We studied 346 patients after bone marrow transplantation (BMT) for chronic myeloid
leukemia (CML) for the presence of the bcr-abl transcript detected by the polymerase chain …

Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …

K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

Frequent detection of BCR-ABL specific mRNA in patients with chronic myeloid leukemia (CML) following allogeneic and syngeneic bone marrow transplantation …

A Gaiger, T Lion, P Kalhs, G Mitterbauer, T Henn… - Leukemia, 1993 - europepmc.org
We performed a two-step polymerase chain reaction (PCR) to detect bcr-abl-specific mRNA
in 440 peripheral blood and/or bone marrow samples of 30 chronic myeloid leukemia (CML) …

Comparison of genomic DNA and cDNA for detection of residual disease after treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation

JG Zhang, F Lin, A Chase, JM Goldman, NC Cross - 1996 - ashpublications.org
To test whether patients in remission after allogeneic bone marrow transplantation (BMT)
possess a pool of chronic myeloid leukemia (CML) cells that do not express BCR-ABL …

Value of PCR analysis for long term survivors after allogeneic bone marrow transplant for chronic myelogenous leukemia: a comparative study

RT Costello, J Kirk, J Gabert - Leukemia & lymphoma, 1996 - Taylor & Francis
At present, allogeneic bone marrow transplantation (BMT) seems to be the only curative
treatment for patients with chronic myeloid leukemia (CML). The mechanisms of this …

Persistence of bcr-abl gene expression following bone marrow transplantation for chronic myelogenous leukemia in chronic phase

DS SNYDER, JJ ROSSI, JLIN WANG… - …, 1991 - journals.lww.com
The bcr-abl RNA transcript is the molecular counterpart of the Philadelphia chromosome
and is detectable by an extremely sensitive polymerase chain reaction assay in most …

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time'quantitative RT-PCR assay

C Preudhomme, F Revillion, A Merlat, L Hornez… - Leukemia, 1999 - nature.com
Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive …

AH Elmaagacli, DW Beelen, B Opalka, S Seeber… - Annals of …, 2000 - Springer
The use of the real-time reverse-transcription polymerase-chain reaction (RT-PCR) method
to quantify BCR-ABL transcripts before and after allogeneic transplant was prospectively …

Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.

CL Sawyers, L Timson, ES Kawasaki… - Proceedings of the …, 1990 - National Acad Sciences
Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …