Oxytocin treatment, circuitry, and autism: a critical review of the literature placing oxytocin into the autism context

AJ Guastella, IB Hickie - Biological psychiatry, 2016 - Elsevier
Observed impairment in reciprocal social interaction is a diagnostic hallmark of autism
spectrum disorders. There is no effective medical treatment for these problems …

Autism and oxytocin: new developments in translational approaches to therapeutics

JJ Green, E Hollander - Neurotherapeutics, 2010 - Springer
Autism is a neurodevelopmental disorder characterized by dysfunction in three core
symptom domains: speech and communication deficits, repetitive or compulsive behaviors …

Clinical and neural effects of six-week administration of oxytocin on core symptoms of autism

T Watanabe, M Kuroda, H Kuwabara, Y Aoki… - Brain, 2015 - academic.oup.com
Autism spectrum disorder is a prevalent neurodevelopmental disorder with no established
pharmacological treatment for its core symptoms. Although previous literature has shown …

Oxytocin and experimental therapeutics in autism spectrum disorders

JA Bartz, E Hollander - Progress in brain research, 2008 - Elsevier
Autism is a developmental disorder characterized by three core symptom domains: speech
and communication abnormalities, social functioning impairments and repetitive behaviours …

Integrative approaches utilizing oxytocin to enhance prosocial behavior: from animal and human social behavior to autistic social dysfunction

H Yamasue, JR Yee, R Hurlemann… - Journal of …, 2012 - Soc Neuroscience
The prevalence of autism spectrum disorder (ASD) is as high as 1 in 100 individuals and is a
heavy burden to society. Thus, identifying causes and treatments is imperative. Here, we …

Promising evidence and remaining issues regarding the clinical application of oxytocin in autism spectrum disorders

H Yamasue - Psychiatry and clinical neurosciences, 2016 - Wiley Online Library
Oxytocin is a potential therapeutic for the core symptoms of autism spectrum disorder (ASD),
which is currently untreatable with pharmacotherapy. Previous clinical trials of a single dose …

Oxytocin and autism spectrum disorders

H Yamasue, G Domes - Behavioral Pharmacology of Neuropeptides …, 2018 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental disorder whose core symptoms
include deficits in social interaction and communication besides restricted and repetitive …

Refining oxytocin therapy for autism: context is key

CL Ford, LJ Young - Nature Reviews Neurology, 2022 - nature.com
A recent clinical trial found no effect of chronic intranasal oxytocin on social behaviour in
children with autism spectrum disorders. The result is not surprising, as oxytocin facilitates …

Oxytocin and autism spectrum disorders: a systematic review and meta-analysis of randomized controlled trials

YP Ooi, SJ Weng, J Kossowsky, H Gerger… - …, 2017 - thieme-connect.com
Aim: Oxytocin presents an exciting potential to target the core symptoms of autism spectrum
disorder (ASD) pharmacologically in an easily administered, cost-effective form with possibly …

Overview of human oxytocin research

KM Kendrick, AJ Guastella, B Becker - Behavioral pharmacology of …, 2018 - Springer
Social dysfunction is a core symptom of many psychiatric disorders and current medications
have little or no remedial effects on this. Following on from extensive studies on animal …