[PDF][PDF] Prospects for admixture mapping of complex traits
PM McKeigue - The American Journal of Human Genetics, 2005 - cell.com
Admixture mapping extends to human populations the principles that underlie linkage
analysis of an experimental cross. For detecting genes that contribute to ethnic variation in …
analysis of an experimental cross. For detecting genes that contribute to ethnic variation in …
[PDF][PDF] Statistical tests for admixture mapping with case-control and cases-only data
G Montana, JK Pritchard - The American Journal of Human Genetics, 2004 - cell.com
Admixture mapping is a promising new tool for discovering genes that contribute to complex
traits. This mapping approach uses samples from recently admixed populations to detect …
traits. This mapping approach uses samples from recently admixed populations to detect …
Admixture mapping comes of age
CA Winkler, GW Nelson… - Annual review of genomics …, 2010 - annualreviews.org
Admixture mapping is based on the hypothesis that differences in disease rates between
populations are due in part to frequency differences in disease-causing genetic variants. In …
populations are due in part to frequency differences in disease-causing genetic variants. In …
Overview of admixture mapping
D Shriner - Current protocols in human genetics, 2017 - Wiley Online Library
Admixture mapping is a powerful method of gene mapping for diseases or traits that show
differential risk by ancestry. Admixture mapping has been applied most often to Americans …
differential risk by ancestry. Admixture mapping has been applied most often to Americans …
Measuring and using admixture to study the genetics of complex diseases
I Halder, MD Shriver - Human genomics, 2003 - Springer
Admixture is an important evolutionary force that can and should be used in efforts to apply
genomic data and technology to the study of complex disease genetics. Admixture linkage …
genomic data and technology to the study of complex disease genetics. Admixture linkage …
[PDF][PDF] A genomewide admixture mapping panel for Hispanic/Latino populations
Admixture mapping (AM) is a promising method for the identification of genetic risk factors
for complex traits and diseases showing prevalence differences among populations …
for complex traits and diseases showing prevalence differences among populations …
[PDF][PDF] Design and analysis of admixture mapping studies
Admixture between populations originating on different continents can be exploited to detect
disease susceptibility loci at which risk alleles are distributed differentially between these …
disease susceptibility loci at which risk alleles are distributed differentially between these …
[PDF][PDF] A high-density admixture map for disease gene discovery in African Americans
MW Smith, N Patterson, JA Lautenberger… - The American Journal of …, 2004 - cell.com
Admixture mapping (also known as" mapping by admixture linkage disequilibrium," or
MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups …
MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups …
Mapping by admixture linkage disequilibrium: advances, limitations and guidelines
MW Smith, SJ O'Brien - Nature Reviews Genetics, 2005 - nature.com
Mapping by admixture linkage disequilibrium (MALD) is a theoretically powerful, although
unproven, approach to mapping genetic variants that are involved in human disease. MALD …
unproven, approach to mapping genetic variants that are involved in human disease. MALD …
Local and global ancestry inference and applications to genetic association analysis for admixed populations
TA Thornton, JL Bermejo - Genetic epidemiology, 2014 - Wiley Online Library
Genetic association studies in recently admixed populations offer exciting opportunities to
identify novel variants underlying phenotypic diversity. At the same time, genetic …
identify novel variants underlying phenotypic diversity. At the same time, genetic …