In recent years, polymer drug carriers based on N-(2-hydroxypropyl) methacrylamide
(HPMA) copolymers with pH-triggered drug release have shown enhanced uptake in solid …

We have recently achieved efficient cytosolic delivery by using pH-sensitive poly (2-
(methacryloyloxy) ethylphosphorylcholine)-co-poly (2-(diisopropylamino) …

A facile synthetic pathway for preparing block copolymers with pH-responsive l-glutamic
acid segments for membrane disruption is reported. Aqueous reversible addition …

To optimize polymer design for tumor directed drug delivery, the fate and the total body
distribution of soluble synthetic macromolecules, derived from copolymers of [(N-2 …

Polyelectrolyte complexation, the combination of anionically and cationically charged
polymers through ionic interactions, can be used to form hydrogel networks. These networks …

The majority of nanoparticles designed for cellular delivery of drugs and imaging agents
enter the cell via endocytotic pathways leading to their entrapment in endosomes that …

We summarize the development and evaluation of new type of phospholipid polymers as a
solubilizer for poorly water-soluble compounds. That is, a water-soluble and amphiphilic …

A series of amphiphilic graft polyphosphazenes with hydrophilic weight fraction ranging from
0.40 to 0.55 were synthesized. These copolymers could self-assemble into distinct …

Targeted delivery of therapeutics to the mitochondria of cells without alteration of drug
properties can be a vital technique in the treatment of a variety of mitochondrial-dysfunction …

Purpose. Intracellular targets sensitive to oxidized damage generated by photodynamic
therapy (PDT) utilizing N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-mesochlorin …