ContextAdvanced heart failure, defined as persistence of limiting symptoms despite therapy
with agents of proven efficacy, accounts for the majority of morbidity and mortality in heart …

Heart failure remains a common diagnosis, especially in older individuals. It continues to be
associated with significant morbidity and mortality, but major advances in both diagnosis …

This article updates the Heart Failure Association of the European Society of Cardiology
(ESC) 2007 classification of advanced heart failure and describes new diagnostic and …

Few conditions in medicine have a prognosis as bleak as chronic heart failure (1, 2), but
recent developments have engendered hope that matters may be improving. There is now a …

Heart failure is a common and growing problem with a poor prognosis both in terms of
morbidity and mortality. Furthermore, the natural history of heart failure can be modified …

Chronic heart failure (CHF) is associated with a heavy burden of disease for patients and
healthcare professionals. Quality of life and long-term prognosis for affected patients remain …

BACKGROUND: A consensus conference was convened to define the current state and
important gaps in knowledge and needed research on “Palliative and Supportive Care in …

Heart failure is a major public health problem, with a patient population of at least 10 million
in Europe and approximately 5 million in North America. 1–3 Because of its age-dependent …

Heart failure (HF) is a syndrome characterized by high mortality, frequent hospitalization,
reduced quality of life, and a complex therapeutic regimen. Knowledge about HF is …

Therapy has improved the survival of heart failure (HF) patients. However, many patients
progress to advanced chronic HF (ACHF). We propose a practical clinical definition and …