OBJECTIVE: To assess whether the risk of medically attended local reactions to the fifth
dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine varies …

OBJECTIVE. Local reactions are relatively common after the fifth diphtheria-tetanus-acellular
pertussis vaccination, but factors associated with an increased risk of those reactions are not …

Background. Since 1997 diphtheria-tetanus toxoids-acellular pertussis (DTaP) vaccines
have been recommended for the five dose pertussis vaccination series. To assess rates of …

Recent reports indicate that children receiving a fifth consecutive dose of DTPa vaccine
have a moderate likelihood of developing a large injection site reaction, the etiology of …

Background: Large injection site reactions commonly follow booster doses of diphtheria-
tetanus-acellular pertussis (DTaP) vaccines at 4–6 years of age. A vaccine with lower …

Background. Acellular pertussis (aP)-containing vaccines cause fewer adverse events than
whole-cell versions for primary doses. Booster doses, however, may be followed by …

Background. Diphtheria and tetanus toxoid combined with acellular pertussis (DTaP)
vaccines are less reactogenic than diphtheria and tetanus toxoid combined with whole cell …

Background: Adult formulation tetanus and diphtheria toxoids and acellular pertussis
vaccines (Tdap) have been developed to prevent pertussis in adolescents and adults. There …

BACKGROUND. The frequency of local vaccination reactions increases with successive
doses of diphtheria-tetanus toxoids-acellular pertussis (DTaP) vaccine, and local reactions …

Background: Safety of a sixth consecutive dose of acellular pertussis vaccine in adolescents
was assessed in a 2-armed, randomized study. Methods: Adolescents who had received 5 …