Long-term exposure to intranasal oxytocin in a mouse autism model

KL Bales, M Solomon, S Jacob, JN Crawley… - Translational …, 2014 - nature.com
Oxytocin (OT) is a neuropeptide involved in mammalian social behavior. It is currently in
clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy …

The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings

DM Cochran, D Fallon, M Hill… - Harvard review of …, 2013 - journals.lww.com
Identify the biological role of oxytocin in forming attachments. Evaluate the relationship
between various neuropsychiatric disorders and oxytocin. Identify clinical implications of …

[PDF][PDF] Interplay between oxytocin and sensory systems in the orchestration of socio-emotional behaviors

V Grinevich, R Stoop - Neuron, 2018 - cell.com
The neuropeptide oxytocin (OT) attracts the interest of neuroscientists, psychologists, and
psychiatrists due to its capacity to modulate emotional and social behavior. Although much …

Low-dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized four-way crossover trial with nasal cavity …

DS Quintana, LT Westlye, ØG Rustan, N Tesli… - Translational …, 2015 - nature.com
Despite the promise of intranasal oxytocin (OT) for modulating social behavior, recent work
has provided mixed results. This may relate to suboptimal drug deposition achieved with …

[HTML][HTML] The oxytocin paradox

RAI Bethlehem, S Baron-Cohen, J van Honk… - Frontiers in behavioral …, 2014 - frontiersin.org
In 2005, Kosfeld et al. published their now seminal paper showing that intranasal oxytocin
(OXT) administration increased interpersonal trust (Kosfeld et al., 2005). This finding …

A brief history of oxytocin and its role in modulating psychostimulant effects

DS Carson, AJ Guastella, ER Taylor… - Journal of …, 2013 - journals.sagepub.com
Over the past century, the polypeptide oxytocin has played an important role in medicine
with major highlights including the identification of its involvement in parturition and the milk …

[HTML][HTML] Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within …

DS Quintana, LT Westlye, D Alnæs, ØG Rustan… - …, 2016 - Elsevier
It is unclear if and how exogenous oxytocin (OT) reaches the brain to improve social
behavior and cognition and what is the optimal dose for OT response. To better understand …

[HTML][HTML] Links between the neurobiology of oxytocin and human musicality

AR Harvey - Frontiers in human neuroscience, 2020 - frontiersin.org
The human species possesses two complementary, yet distinct, universal communication
systems—language and music. Functional imaging studies have revealed that some core …

Assembling the puzzle: pathways of oxytocin signaling in the brain

V Grinevich, HS Knobloch-Bollmann, M Eliava… - Biological …, 2016 - Elsevier
Oxytocin (OT) is a neuropeptide, which can be seen to be one of the molecules of the
decade due to its profound prosocial effects in nonvertebrate and vertebrate species …

[HTML][HTML] The role of intranasal oxytocin in anxiety and depressive disorders: A systematic review of randomized controlled trials

F De Cagna, L Fusar-Poli, S Damiani… - Clinical …, 2019 - ncbi.nlm.nih.gov
Several studies have demonstrated the neuromodulating function of oxytocin (OT) in
response to anxiogenic stimuli as well as its potential role in the pathogenesis of …