Kinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men

J Lieberz, D Scheele, FB Spengler… - …, 2020 - nature.com
Accumulating evidence suggests that intranasal oxytocin (OXT; 24 IU) reduces amygdala
responses to fear-related stimuli in men, while exerting inverse effects in women. However …

Oxytocin specifically enhances valence-dependent parasympathetic responses

M Gamer, C Büchel - Psychoneuroendocrinology, 2012 - Elsevier
The evolutionarily highly conserved neuropeptide oxytocin seems to be involved in the
regulation of complex forms of social behavior. It enhances the processing of positive social …

A meta-analytic review of the impact of intranasal oxytocin administration on cortisol concentrations during laboratory tasks: moderation by method and mental health

C Cardoso, D Kingdon, MA Ellenbogen - Psychoneuroendocrinology, 2014 - Elsevier
Background A large body of research has examined the acute effects of intranasal oxytocin
administration on social cognition and stress-regulation. While progress has been made …

Oxytocin in the socioemotional brain: implications for psychiatric disorders

P Kirsch - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The neuropeptide oxytocin (OXT), highly conserved during evolution, is an important
modulator of social and emotional processes across many species. During the last decade …

Intranasal oxytocin administration attenuates the ACTH stress response in monkeys

KJ Parker, CL Buckmaster, AF Schatzberg… - …, 2005 - Elsevier
Social relationships protect against the development of stress-related psychiatric disorders,
yet little is known about the neurobiology that regulates this phenomenon. Recent evidence …

A general approach-avoidance hypothesis of oxytocin: accounting for social and non-social effects of oxytocin

O Harari-Dahan, A Bernstein - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Background We critically reexamine extant theory and empirical study of Oxytocin. We
question whether OT is, in fact, a “social neuropeptide” as argued in dominant theories of …

Oxytocin enhances processing of positive versus negative emotional information in healthy male volunteers

M Di Simplicio, R Massey-Chase… - Journal of …, 2009 - journals.sagepub.com
Animal studies have shown the role of oxytocin in affiliation and attachment, and recent
evidence suggests that oxytocin is also involved in human models of approach behaviour …

Oxytocin facilitates the sensation of social stress

M Eckstein, D Scheele, K Weber… - Human brain …, 2014 - Wiley Online Library
Essentially all social species experience social stress which can be a catalyst for detriments
in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce …

Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans

M Gamer, B Zurowski, C Büchel - Proceedings of the …, 2010 - National Acad Sciences
The neuropeptide oxytocin enhances the processing of positive social stimuli and improves
the capacity to effectively attend the eye region of conspecifics. To investigate the neural …

Fear-enhancing effects of septal oxytocin receptors

YF Guzmán, NC Tronson, V Jovasevic, K Sato… - Nature …, 2013 - nature.com
The nonapeptide oxytocin is considered beneficial to mental health due to its anxiolytic,
prosocial and antistress effects, but evidence for anxiogenic actions of oxytocin in humans …