Non-small-cell lung cancers: a heterogeneous set of diseases

Z Chen, CM Fillmore, PS Hammerman, CF Kim… - Nature Reviews …, 2014 - nature.com
Non-small-cell lung cancers (NSCLCs), the most common lung cancers, are known to have
diverse pathological features. During the past decade, in-depth analyses of lung cancer …

[HTML][HTML] The emerging treatment landscape of advanced non-small cell lung cancer

P Economopoulou, G Mountzios - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
Lung cancer remains the leading cause of cancer related death worldwide. Despite broad
advances in diagnostics and therapy, the five-year overall survival for patients with …

[HTML][HTML] Targeted therapies in development for non-small cell lung cancer

T Reungwetwattana, GK Dy - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
The iterative discovery in various malignancies during the past decades that a number of
aberrant tumorigenic processes and signal transduction pathways are mediated by …

Therapeutic advances in non‐small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy

Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
Lung cancer still contributes to nearly one‐quarter cancer‐related deaths in the past
decades, despite the rapid development of targeted therapy and immunotherapy in non …

The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …

Current landscape of non-small cell lung cancer: epidemiology, histological classification, targeted therapies, and immunotherapy

O Rodak, MD Peris-Díaz, M Olbromski… - Cancers, 2021 - mdpi.com
Simple Summary The abundance and the dynamic of the studies on NSCLC require
frequent summaries of the current achievements in the field. In our review, we aimed to …

Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents

T Singh, MF Hassanabad, AF Hassanabad - Biochimica et Biophysica Acta …, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) represents the most common and fatal type of primary
lung malignancies. NSCLC is often diagnosed at later stages and requires systemic …

[HTML][HTML] Molecularly targeted therapies in non–small-cell lung cancer annual update 2014

D Morgensztern, MJ Campo, SE Dahlberg… - Journal of Thoracic …, 2015 - Elsevier
There have been significant advances in the understanding of the biology and treatment of
non–small-cell lung cancer (NSCLC) during the past few years. A number of molecularly …

The biology and management of non-small cell lung cancer

RS Herbst, D Morgensztern, C Boshoff - Nature, 2018 - nature.com
Important advancements in the treatment of non-small cell lung cancer (NSCLC) have been
achieved over the past two decades, increasing our understanding of the disease biology …

Toward personalized treatment approaches for non-small-cell lung cancer

M Wang, RS Herbst, C Boshoff - Nature medicine, 2021 - nature.com
Worldwide, lung cancer is the most common cause of cancer-related deaths. Molecular
targeted therapies and immunotherapies for non-small-cell lung cancer (NSCLC) have …