Mechanism of lung injury caused by PM10 and ultrafine particles with special reference to COPD
W MacNee, K Donaldson - European Respiratory Journal, 2003 - Eur Respiratory Soc
Particulate air pollution (particles with a 50% cut-off aerodynamic diameter of 10 µm (PM
10)) has strong associations with the adverse health events detected by epidemiological …
10)) has strong associations with the adverse health events detected by epidemiological …
Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10)
K Donaldson, W MacNee - … Journal of Hygiene and Environmental Health, 2001 - Elsevier
PM10 is the international convention for measuring environmental particulate air pollution.
Increases in PM10 have been linked to exacerbations of airways disease and deaths from …
Increases in PM10 have been linked to exacerbations of airways disease and deaths from …
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung
E André, T Stoeger, S Takenaka… - European …, 2006 - Eur Respiratory Soc
High levels of particulate matter in ambient air are associated with increased respiratory and
cardiovascular health problems. It has been hypothesised that it is the ultrafine particle …
cardiovascular health problems. It has been hypothesised that it is the ultrafine particle …
Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro.
XY Li, PS Gilmour, K Donaldson, W MacNee - Thorax, 1996 - thorax.bmj.com
BACKGROUND: Epidemiological evidence has implicated fine particulate air pollution,
particularly particles less than 10 microns in diameter (PM10), in the development of …
particularly particles less than 10 microns in diameter (PM10), in the development of …
The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types
PM 10 contains an ultrafine component, which is generally derived from combustion
processes. This ultrafine fraction may be a factor in the increases in exacerbations of …
processes. This ultrafine fraction may be a factor in the increases in exacerbations of …
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium
Background Particulate air pollution is reported to cause adverse health effects in
susceptible individuals. Since most of these particles are derived form combustion …
susceptible individuals. Since most of these particles are derived form combustion …
The pulmonary toxicology of ultrafine particles
Ultrafine particles are a component of air pollution, derived from primary combustion
sources, and so we have undertaken a programme of study on the mechanisms of lung …
sources, and so we have undertaken a programme of study on the mechanisms of lung …
Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin
A CP Elder, R Gelein, J N. Finkelstein, C Cox… - Inhalation …, 2000 - Taylor & Francis
Epidemiological studies demonstrate associations between increasing levels of ambient
particles and morbidity in the elderly with cardiopulmonary disease. Such findings have …
particles and morbidity in the elderly with cardiopulmonary disease. Such findings have …
Reactive oxygen species in pulmonary inflammation by ambient particulates
F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …
Pulmonary effects of inhaled ultrafine particles
G Oberdörster - … archives of occupational and environmental health, 2000 - Springer
Abstract Introduction and Objectives: Recent epidemiological studies have shown an
association between increased particulate urban air pollution and adverse health effects on …
association between increased particulate urban air pollution and adverse health effects on …