A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain

M Taipale, N Kaminen… - Proceedings of the …, 2003 - National Acad Sciences
Approximately 3–10% of people have specific difficulties in reading, despite adequate
intelligence, education, and social environment. We report here the characterization of a …

SNP Variations in the 7q33 Region Containing DGKI are Associated with Dyslexia in the Finnish and German Populations

H Matsson, K Tammimies, M Zucchelli, H Anthoni… - Behavior genetics, 2011 - Springer
Abstract Four genes, DYX1C1, ROBO1, DCDC2 and KIAA0319 have been studied both
genetically and functionally as candidate genes for developmental dyslexia, a common …

Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21

IR König, J Schumacher, P Hoffmann… - American Journal of …, 2011 - Wiley Online Library
In a genome‐wide linkage scan, we aimed at mapping risk loci for dyslexia in the German
population. Our sample comprised 1,030 individuals from 246 dyslexia families which were …

Confirmation of dyslexia susceptibility loci on chromosomes 1p and 2p, but not 6p in a Dutch sib‐pair collection

CGF De Kovel, B Franke, FA Hol… - American Journal of …, 2008 - Wiley Online Library
In this study, we attempted to confirm genetic linkage to developmental dyslexia and reading‐
related quantitative traits of loci that have been shown to be associated with dyslexia in …

Association of the DYX1C1 Dyslexia Susceptibility Gene with Orthography in the Chinese Population

Y Zhang, J Li, T Tardif, M Burmeister, SM Villafuerte… - 2012 - journals.plos.org
Several independent studies have supported the association of DYX1C1 with dyslexia, but
its role in general reading development remains unclear. Here, we investigated the …

Deficits in learning and memory in mice with a mutation of the candidate dyslexia susceptibility gene Dyx1c1

AR Rendall, A Tarkar, HM Contreras-Mora… - Brain and language, 2017 - Elsevier
Dyslexia is a learning disability characterized by difficulty learning to read and write. The
underlying biological and genetic etiology remains poorly understood. One candidate gene …

Genetics of dyslexia: the evolving landscape

J Schumacher, P Hoffmann, C Schmäl… - Journal of medical …, 2007 - jmg.bmj.com
Dyslexia is among the most common neurodevelopmental disorders, with a prevalence of 5–
12%. At the phenotypic level, various cognitive components that enable reading and …

Developmental dyslexia: an update

BS Shastry - Journal of Human Genetics, 2007 - nature.com
Dyslexia is the most common and carefully studied of the learning disabilities in school-age
children. It is characterized by a marked impairment in the development of reading skills …

[PDF][PDF] A 77-kilobase region of chromosome 6p22. 2 is associated with dyslexia in families from the United Kingdom and from the United States

C Francks, S Paracchini, SD Smith… - The American Journal of …, 2004 - cell.com
Several quantitative trait loci (QTLs) that influence developmental dyslexia (reading
disability [RD]) have been mapped to chromosome regions by linkage analysis. The most …

Genomewide scan identifies susceptibility locus for dyslexia on Xq27 in an extended Dutch family

CGF De Kovel, FA Hol, J Heister, J Willemen… - Journal of medical …, 2004 - jmg.bmj.com
Context: Dyslexia is a common disorder with a strong genetic component, but despite
significant research effort, the aetiology is still largely unknown. Objective: To identify loci …