The current scenario of naturally occurring indole alkaloids with anticancer potential

J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
Naturally occurring indole alkaloids are ubiquitously present in nature and possess
extensive biological properties and structural diversity. Mechanistically, naturally occurring …

Indole alkaloids with potential anticancer activity

D Xu, Z Xu - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
Indole alkaloids, which are abundant in nature, are a significant source of pharmacologically
active compounds. Indole alkaloids have the potential to exert anticancer activity via various …

Indole-containing natural products 2019–2022: isolations, reappraisals, syntheses, and biological activities

SM Umer, M Solangi, KM Khan, RSZ Saleem - Molecules, 2022 - mdpi.com
Indole alkaloids represent a large subset of natural products, with more than 4100 known
compounds. The majority of these alkaloids are biologically active, with some exhibiting …

Indole alkaloids, synthetic dimers and hybrids with potential in vivo anticancer activity

F Song, Y Bian, J Liu, Z Li, L Zhao… - Current Topics in …, 2021 - ingentaconnect.com
Indole, a heterocyclic organic compound, is one of the most promising heterocycles found in
natural and synthetic sources since its derivatives possess fascinating structural diversity …

[PDF][PDF] Indoles as anti-cancer agents. Adv Mod Oncol Res 2015; 1 (1): 20–35

MT El Sayed, NA Hamdy, DA Osman - 2011 - scholar.archive.org
Indoles are natural products which are well known for its anti-cancer activity due to its ability
to induce cell death for many cancer cell lines. This review addresses indoles as natural …

[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers

F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
Cancer is the leading cause of mortality all over the world. Scientific investigation has
demonstrated that disruptions in the process of autophagy are frequently interrelated with …

Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets

R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
Regulated cell death (RCD) is a critical and active process that is controlled by specific
signal transduction pathways and can be regulated by genetic signals or drug interventions …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

M Ishikura, T Abe, T Choshi, S Hibino - Natural product reports, 2015 - pubs.rsc.org
Covering: 2012 to 2013. Previous review: Nat. Prod. Rep., 2013, 30, 694–752 This review
covers the literature on simple indole alkaloids and those with a nonrearranged …

Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities

PF Rosales, GS Bordin, AE Gower, S Moura - Fitoterapia, 2020 - Elsevier
Indole alkaloids have attracted attention because of their therapeutic properties, being anti-
inflammatory, antinociceptive, antitumoural, antioxidant and antimicrobial. These …