The number of growth factors involved in female fertility has been extensively studied, but
reluctance to add essential growth factors in culture media has limited progress in optimizing …

The role of the insulin-like growth factor (IGF) system has attracted close attention. The
activity of IGF binding proteins (IGFBPs) within the ovary has not been fully elucidated to …

Objective: To review the available information regarding the roles of insulin‐like growth
factor (IGF)‐IGF binding protein (IGFBP) system in ovarian physiology. Design: Studies that …

The insulin-like growth factors (IGF-I and-II) are ubiquitously expressed factors that regulate
cell growth, differentiation and maintenance of differentiated cell function. All aspects of male …

We investigated the effects of insulin-like growth factor 1 (IGF-1) on the morphology and
follicular activation of ovine preantral follicles cultured in situ and whether the …

Background Insulin-like growth factor (IGF) has unique and well-known functions in female
fertility, according to documents reporting improved yield of oocytes, reinforced quality of the …

There is increasing evidence that growth factors modulate folliculogenesis. However their
precise role in the processes of follicular growth, differentiation and atresia is still unknown …

PROBLEM: Insulin‐like growth factors (IGFs) and insulin have been demonstrated to
stimulate oocyte maturation and embryo development. Therefore, the expression of IGFs …

Growth hormone (GH) has gained attention as an anti-aging compound enhancing oocyte
quality. In fact, GH is known to activate intrafollicular metabolic events for oocyte maturation …

Oocyte maturation is critical for successful fertilization and pregnancy. The mechanism
underlying the control of this complex process remain relatively unknown, and even more so …