Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development
S Takahashi, A Ishida, A Kubo, H Kawasaki, S Ochiai… - Scientific reports, 2019 - nature.com
The epidermal barrier is thought to protect sensory nerves from overexposure to
environmental stimuli, and barrier impairment leads to pathological conditions associated …
environmental stimuli, and barrier impairment leads to pathological conditions associated …
Molecular mechanisms of cutaneous inflammatory disorder: atopic dermatitis
JE Kim, JS Kim, DH Cho, HJ Park - International journal of molecular …, 2016 - mdpi.com
Atopic dermatitis (AD) is a multifactorial inflammatory skin disease resulting from interactions
between genetic susceptibility and environmental factors. The pathogenesis of AD is poorly …
between genetic susceptibility and environmental factors. The pathogenesis of AD is poorly …
Multifactorial skin barrier deficiency and atopic dermatitis: Essential topics to prevent the atopic march
G Egawa, K Kabashima - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Atopic dermatitis (AD) is the most common inflammatory skin disease in the industrialized
world and has multiple causes. Over the past decade, data from both experimental models …
world and has multiple causes. Over the past decade, data from both experimental models …
Tight junction proteins expression and modulation in immune cells and multiple sclerosis
I Mandel, T Paperna, L Glass‐Marmor… - Journal of cellular …, 2012 - Wiley Online Library
The tight junction proteins (TJPs) are major determinants of endothelial cells comprising
physiological vascular barriers such as the blood–brain barrier, but little is known about their …
physiological vascular barriers such as the blood–brain barrier, but little is known about their …
NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation
The skin of patients with atopic dermatitis (AD) has a unique predisposition for colonization
by Staphylococcus aureus (S. aureus), which contributes to the inflammation and grim …
by Staphylococcus aureus (S. aureus), which contributes to the inflammation and grim …
Differential expression and function of bicellular tight junctions in skin and oral wound healing
TR Leonardo, J Shi, D Chen, HM Trivedi… - International Journal of …, 2020 - mdpi.com
Bicellular tight junctions are multiprotein complexes that are required for maintenance of
barrier function and fence function in epithelial tissues. Wound healing in the oral cavity …
barrier function and fence function in epithelial tissues. Wound healing in the oral cavity …
Inflammation‐driven dermal lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment and VEGF‐C up‐regulation in the IL‐4 …
VY Shi, L Bao, LS Chan - Microcirculation, 2012 - Wiley Online Library
Please cite this paper as: Shi VY, Bao L, Chan LS. Inflammation‐driven dermal
lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment …
lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment …
[HTML][HTML] Regulation of epidermal tight-junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains
U Ohnemus, K Kohrmeyer, P Houdek, H Rohde… - Journal of Investigative …, 2008 - Elsevier
Tight Junction (TJ) proteins have been shown to exert a barrier function within the skin.
Here, we study the fate of TJ proteins during the challenge of the skin by bacterial …
Here, we study the fate of TJ proteins during the challenge of the skin by bacterial …
[HTML][HTML] Integrin αE (CD103) is involved in regulatory T-cell function in allergic contact hypersensitivity
A Braun, N Dewert, F Brunnert, V Schnabel… - Journal of Investigative …, 2015 - Elsevier
Murine contact hypersensitivity (CHS) is a dendritic cell (DC)-dependent T-cell-mediated
inflammation with CD8+ T cells as effectors and CD4+ T cells as regulators (Treg cells) that …
inflammation with CD8+ T cells as effectors and CD4+ T cells as regulators (Treg cells) that …
Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity
K Wang, Y Ding, C Xu, M Hao, H Li, L Ding - Oncoimmunology, 2021 - Taylor & Francis
Intestinal epithelial barrier protects intestine from infection and injury, while chronic
inflammation is a trigger for tumorigenesis. As a member of tight junctions (TJs) family …
inflammation is a trigger for tumorigenesis. As a member of tight junctions (TJs) family …