B cells, plasma cells, and antibodies are commonly found in active central nervous system
(CNS) lesions in patients with multiple sclerosis (MS). B cells isolated from CNS lesions as …

Clonal expansion of B cells and the production of oligoclonal IgG in the brain and
cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) have long been interpreted …

Multiple sclerosis (MS) is a widespread neurodegenerative autoimmune disease with
unknown etiology. It is increasingly evident that, together with pathogenic T cells …

Plasmablasts are a highly differentiated, antibody secreting B cell subset whose prevalence
correlates with disease activity in Multiple Sclerosis (MS). For most patients experiencing …

Immunoglobulin G, A, and M (IgG, IgA, and IgM) were purified from multiple sclerosis (MS)
cerebrospinal fluid (CSF) and sera and analyzed by two-dimensional electrophoresis. The …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of unknown cause
that afflicts the central nervous system. MS is typified by a highly clonally restricted antigen …

We have shown earlier that CD8+ T cell oligoclonality occurs frequently in normal
individuals and generally exhibits a very diverse repertoire. In order to investigate the role of …

B cells have long played an enigmatic role in the scenario of multiple sclerosis
pathogenesis. This review summarizes recent progress in our understanding of B‐cell …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS), with characteristic inflammatory lesions and demyelination. The clinical benefit of cell …

T‐cell populations were investigated in the blood and cerebrospinal fluid of patients with
multiple sclerosis and other neurological diseases. Individual T cells were directly cloned …