Distribution, level, pharmacology, regulation, and signaling of 5‐HT6 receptors in rats and marmosets with special reference to an experimental model of …

X Zhang, PE Andren, RA Glennon… - Journal of …, 2011 - Wiley Online Library
Serotonin 5‐HT6 receptors have been implicated in the regulation of cognition, locomotion,
and mood, but the elucidation of their functions is complicated by conflicting data using …

Differential effects of selective lesions of cholinergic and dopamingergic neurons on serotonin‐type 1 receptors in rat brain

R Quirion, J Richard - Synapse, 1987 - Wiley Online Library
Abstract Serotonin (5‐HT)‐type1 (abbreviated as a subscript 1) receptor binding sites are
discretely distributed in rat brain. High densities of [3H] 5‐HT1 binding sites are especially …

Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics

C Bombardi, A Grandis, N Pivac, M Sagud… - Progress in brain …, 2021 - Elsevier
The hippocampal region receives a dense serotoninergic innervation originating from both
medial and dorsal raphe nuclei. This innervation regulates hippocampal activity through the …

Direct visualization of serotonin1D receptors in the human brain using a new iodinated radioligand

JM Palacios, C Waeber, AT Bruinvels, D Hoyer - Molecular brain research, 1992 - Elsevier
The development of the new ligand serotonin-5-O-carboxymethyl-glycyl [125 I] tyrosinamide
(abbreviated [125 I] GTI) allows for the direct visualization of serotonin 1B and serotonin 1D …

Serotonin receptors, type 4: a new hope?

G Lucas - Current drug targets, 2009 - ingentaconnect.com
Serotonin4 (5-HT4) receptors have been shown to be involved in several peripheral and
central functions, including control of the gastro-intestinal tract, modulation of memory and …

5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims/depressives: increase in 5-HT2 sites in cortex and amygdala

PD Hrdina, E Demeter, TB Vu, P Sótónyi, M Palkovits - Brain research, 1993 - Elsevier
The density (B max) of 5-HT 2 receptors labelled with [3 H] ketanserin was significantly
increased in prefrontal cortex (by 67%) and amygdala (by 97%) from suicide/depressives in …

5-HT1A/5-HT7 receptor interplay: Chronic activation of 5-HT7 receptors decreases the functional activity of 5-HT1A receptor and its сontent in the mouse brain

EM Kondaurova, DV Bazovkina, VS Naumenko - Molecular Biology, 2017 - Springer
Serotonin receptors 5-HT 1A and 5-HT 7 are involved in the development of various
psychopathologies. Some data indicate that there is an interplay between 5-HT 1A 5-HT 7 …

The distribution of 5-HT6 receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT6 receptor antagonist [125I] SB-258585

JC Roberts, C Reavill, SZ East, PJ Harrison, S Patel… - Brain research, 2002 - Elsevier
We used the highly selective 5-HT6 receptor radioligand [125I] SB-258585 (4-iodo-N-[4-
methoxy-3-(4-methylpiperazin-1-yl) phenyl] benzene-sulfonamide) to perform …

Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations

R Peñas-Cazorla, MT Vilaró - Brain Structure and Function, 2015 - Springer
Activation of serotonin 5-HT 4 receptors has pro-cognitive effects on memory performance.
The proposed underlying neurochemical mechanism is the enhancement of acetylcholine …

Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas

E Marvin, K Scrogin, B Dudás - Journal of chemical neuroanatomy, 2010 - Elsevier
Disorders of serotonergic neurotransmission are involved in disturbances of numerous
hypothalamic functions including circadian rhythm, mood, neuroendocrine functions, sleep …