Brain 5-HT2 receptor binding sites in depressed suicide victims

SC Cheetham, MR Crompton, CLE Katona, RW Horton - Brain research, 1988 - Elsevier
HT 2 receptor binding sites were measured (by saturation binding of [3 H] ketanserin) in
brain tissue obtained at postmortem from 19 suicide victims with definite evidence of …

[PDF][PDF] The 5-HT6 receptor antagonism approach in Alzheimer

D Marazziti, G Rutigliano - Drugs of the Future, 2014 - researchgate.net
SUMMARY Recently, the 5-hydroxytryptamine 5-HT6 receptor has attracted increasing
attention. This receptor is quite different from all other 5-HT receptors, as it includes a short …

Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken

S Hamada, K Senzaki, K Hamaguchi-Hamada… - Molecular brain …, 1998 - Elsevier
Serotonin 2A receptor (5-HT2A receptor) is widely distributed in the central nervous system,
and has been suggested to be involved in a variety of behavioral conditions and …

Regional distribution and ontogeny of 5-HT4 binding sites in rodent brain

C Waeber, M Sebben, A Nieoullon, J Bockaert… - …, 1994 - Elsevier
We have investigated the regional distribution of 5-hydroxytryptamine 4 (5-HT 4) receptor
binding sites in the adult guinea pig, rat and mouse brain using the specific 5-HT 4 …

Serotonin 1A receptors in human and monkey prefrontal cortex are mainly expressed in pyramidal neurons and in a GABAergic interneuron subpopulation …

J De Almeida, G Mengod - Journal of neurochemistry, 2008 - Wiley Online Library
Abstract Serotonin 1A (5‐HT1A) receptors are found in high densities in prefrontal cortex.
However, their distribution within cortical cell populations is unknown in both humans and …

Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain

DE Wright, KB Seroogy, KH Lundgren… - Journal of …, 1995 - Wiley Online Library
Abstract Serotonin (5‐HT) mediates its effects on neurons in the central nervous system
through a number of different receptor types. To gain better insight as to the localization of 5 …

Effects of 5-HT-7 receptor ligands on memory and cognition

N Zareifopoulos, C Papatheodoropoulos - Neurobiology of learning and …, 2016 - Elsevier
The 5-HT7R is the most recently cloned serotonin receptor and thus one the least studied.
Many drugs, experimental and in clinical use bind to 5-HT7 with high affinity, though their …

Cellular and subcellular distribution of the serotonin 5‐HT2A receptor in the central nervous system of adult rat

V Cornea‐Hébert, M Riad, C Wu… - Journal of …, 1999 - Wiley Online Library
Light and electron microscope immunocytochemistry with a monoclonal antibody against the
N‐terminal domain of the human protein was used to determine the cellular and subcellular …

Quantitative analysis of glutamatergic and GABAergic neurons expressing 5‐HT2A receptors in human and monkey prefrontal cortex

J De Almeida, G Mengod - Journal of neurochemistry, 2007 - Wiley Online Library
hydroxytryptamine (5‐HT) or serotonin 2A receptors play an important role in modulation of
prefrontal cortex (PFC) activity and have been implicated in the physiopathology of …

Serotonin1A receptors are increased in postmortem prefrontal cortex in schizophrenia

T Sumiyoshi, CA Stockmeier, JC Overholser, GE Dilley… - Brain research, 1996 - Elsevier
Serotonin-5-HT1A receptors were measured with [3H] 8-hydroxy-2-(di-n-propyl)
aminotetralin ([3H] 8-OH-DPAT) in postmortem prefrontal cortex of 12 pairs of subjects with …