Regional changes in density of serotonin transporter in the brain of 5‐HT1A and 5‐HT1B knockout mice, and of serotonin innervation in the 5‐HT1B knockout

AR Ase, TA Reader, R Hen, M Riad… - Journal of …, 2001 - Wiley Online Library
5‐HT1A knockout (KO) mice display an anxious‐like phenotype, whereas 5‐HT1B KOs are
over‐aggressive. To identify serotoninergic correlates of these altered behaviors …

Central 5-HT1A receptors: regional distribution and functional characteristics

L Lanfumey, M Hamon - Nuclear medicine and biology, 2000 - Elsevier
Among the multiple receptors for serotonin identified to date, the 5-hydroxytryptamine (5-HT)
1A type is among the best known because selective ligands have been available for more …

Quantitative autoradiographic mapping of serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in the neocortex of the rhesus monkey

MS Lidow, PS Goldman‐Rakic… - Journal of …, 1989 - Wiley Online Library
The in vitro autoradiographic technique was used to characterize the distribution of
serotonin 5‐HT1 and 5‐HT2 receptors and uptake sites in 11 cortical areas of frontal …

[3H]Ketanserin Binding in Human Brain Postmortem

D Marazziti, A Rossi, L Palego, G Giannaccini… - Neurochemical …, 1997 - Springer
This study aimed at comparing the binding characteristics of [3 H] ketanserin, a high-affinity
serotonin 2A (5-HT 2A) receptor antagonist, in the prefrontal cortex, hippocampus and …

The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain

PWJ Burnet, SL Eastwood, K Lacey, PJ Harrison - Brain research, 1995 - Elsevier
We have examined the distribution of 5-HT1A and 5-HT2A receptor mRNAs in post-mortem
human hippocampus, neocortex, raphe nuclei, cerebellum and basal ganglia using in situ …

Effect of aging in human cortical pre-and postsynaptic serotonin binding sites

A Eriksson, E Mellerup, P Plenge, J Marcusson - Brain research, 1993 - Elsevier
HT 1A, 5-HT 1D, 5-HT 2 binding sites and affinity and 5-HT uptake sites were simultaneously
determined in frontal cortex samples from 23 control subjects, aged 16–75 years. A …

Computer-assisted autoradiographic localization of subtypes of serotonin1 receptors in rat brain

PP Deshmukh, HI Yamamura, L Woods, DL Nelson - Brain Research, 1983 - Elsevier
In vitro light microscopic receptor autoradiography was carried out to localize two subtypes
of 5-HT 1 receptors in certain regions of the rat central nervous system (CNS). The data were …

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

A Pazos, JM Palacios - Brain research, 1985 - Elsevier
The distribution of serotonin-1 (5-HT 1) receptors in the rat brain was studied by light
microscopic quantitative autoradiography. Receptors were labeled with [3 H] serotonin (5-[3 …

Serotonin receptor diversity in the human colon: expression of serotonin type 3 receptor subunits 5‐HT3C, 5‐HT3D, and 5‐HT3E

J Kapeller, D Möller, F Lasitschka… - Journal of …, 2011 - Wiley Online Library
Since the first description of 5‐HT3 receptors more than 50 years ago, there has been
speculation about the molecular basis of their receptor heterogeneity. We have cloned the …

Htr2a Gene and 5-HT2A Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice

ET Weber, R Andrade - Frontiers in neuroscience, 2010 - frontiersin.org
Serotonin receptors of the 5-HT2A subtype are robustly expressed in the cerebral cortex
where they have been implicated in the pathophysiology and therapeutics of mental …