Genetic variations and normal fetal growth

DB Dunger, CJ Petry, KK Ong - Hormone Research, 2006 - karger.com
Size at birth is said to be a highly heritable trait, with an estimated 30–70% of the variability a
result of genetics. Data from family studies may be confounded, however, by potential …

Birth weight, infant growth and insulin resistance

KK Ong, DB Dunger - European journal of endocrinology, 2004 - academic.oup.com
Size at birth and early postnatal growth rates are important determinants of human perinatal
survival; they also predict the tempo of growth, adult height and long-term risks for obesity …

Genetic determinants of low birth weight.

T Mallia, A Grech, A Hili, J Calleja-Agius… - Minerva …, 2017 - europepmc.org
Birth weight depends on the elaborate interaction between maternal and fetal genotypes,
placental function, maternal nutrition and lifestyle and their effect on epigenetic regulators of …

The role of the insulin-like growth factor system in prenatal growth

R Randhawa, P Cohen - Molecular genetics and metabolism, 2005 - Elsevier
Fetal growth is a complex process involving multiple environmental and genetic factors.
Fetal growth restriction is associated with morbidity among small for gestational age (SGA) …

Genetic factors contributing to birth weight

LB Johnston, AJL Clark, MO Savage - Archives of Disease in Childhood …, 2002 - fn.bmj.com
Fetal genes Insight into the genes that may be involved in human fetal growth has been
provided by studies on human and animal fetal physiology. In particular, mouse gene …

Significance of birth weight for the future

CM Law - Archives of Disease in Childhood-Fetal and Neonatal …, 2002 - fn.bmj.com
Fetal genes Insight into the genes that may be involved in human fetal growth has been
provided by studies on human and animal fetal physiology. In particular, mouse gene …

Insulin‐like growth factor 2 (IGF2) and IGF2 receptor gene variants are associated with fetal growth

K Kaku, H Osada, K Seki, S Sekiya - Acta Paediatrica, 2007 - Wiley Online Library
Aim: Normal variation in size at birth is a result of the interaction between fetal genetic
factors and the maternal uterine environment. It is, however, unclear how genetic factors …

Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study

JJM Geelhoed, DO Mook‐Kanamori… - Clinical …, 2008 - Wiley Online Library
Objective The objective of this study was to examine whether variants of the IGF1 gene are
associated with growth patterns from foetal life until infancy. Study design and …

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans

CJ Petry, KK Ong, BJ Barratt, D Wingate, HJ Cordell… - BMC genetics, 2005 - Springer
Background Common genetic variation at genes that are imprinted and exclusively
maternally expressed could explain the apparent maternal-specific inheritance of low …

Fetal programming of the growth hormone–insulin-like growth factor axis

RIG Holt - Trends in Endocrinology & Metabolism, 2002 - cell.com
Epidemiological studies have shown that small body size at birth and during infancy is
associated with increased rates of chronic diseases in adulthood, including cardiovascular …