Papillary thyroid carcinoma with high-grade features versus poorly differentiated thyroid carcinoma: an analysis of clinicopathologic and molecular features and …
KS Wong, F Dong, M Telatar, JH Lorch, EK Alexander… - Thyroid, 2021 - liebertpub.com
Background: Similar to poorly differentiated thyroid carcinoma (PDTC), papillary thyroid
carcinoma with high-grade features (PTC HGF) demonstrates increased mitotic activity …
carcinoma with high-grade features (PTC HGF) demonstrates increased mitotic activity …
Risk assessment for distant metastasis in differentiated thyroid cancer using molecular profiling: a matched case‐control study
L Yip, WE Gooding, A Nikitski, AI Wald, SE Carty… - Cancer, 2021 - Wiley Online Library
Background Risk stratification for patients with differentiated thyroid cancer (DTC) is based
primarily on pathologic tumor characteristics. Accurate preoperative prognostication could …
primarily on pathologic tumor characteristics. Accurate preoperative prognostication could …
Molecular prognostic markers in papillary and follicular thyroid cancer: Current status and future directions
D Handkiewicz-Junak, A Czarniecka… - Molecular and cellular …, 2010 - Elsevier
Gene expression profiling shows that, by gene signature, the difference between BRAF-
positive and BRAF-negative PTC is so distinct that BRAF-positive cancer may be regarded …
positive and BRAF-negative PTC is so distinct that BRAF-positive cancer may be regarded …
[HTML][HTML] Emerging biomarkers in thyroid practice and research
Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …
evaluable characteristics. These help in perfecting patient management. Over the past …
[HTML][HTML] TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors
M Matsuse, T Yabuta, V Saenko, M Hirokawa… - Scientific reports, 2017 - nature.com
Although most papillary thyroid carcinomas (PTCs) have a good prognosis, a small but
certain fraction shows aggressive behavior. Therefore, a novel and well-performing …
certain fraction shows aggressive behavior. Therefore, a novel and well-performing …
Risk stratification in differentiated thyroid cancer: from detection to final follow-up
RM Tuttle, AS Alzahrani - The Journal of Clinical Endocrinology …, 2019 - academic.oup.com
Context Modern management of differentiated thyroid cancer requires individualized care
plans that tailor the intensity of therapy and follow-up to the estimated risks of recurrence …
plans that tailor the intensity of therapy and follow-up to the estimated risks of recurrence …
The predictive value of coexisting BRAFV600E and TERT promoter mutations on poor outcomes and high tumour aggressiveness in papillary thyroid carcinoma: A …
B Chen, Y Shi, Y Xu, J Zhang - Clinical endocrinology, 2021 - Wiley Online Library
BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
Prognostic factors in papillary and follicular thyroid carcinoma: their implications for cancer staging
Background Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) are
two distinct histological types of thyroid carcinoma but have often been studied and staged …
two distinct histological types of thyroid carcinoma but have often been studied and staged …
Papillary Thyroid Carcinomas with Cervical Lymph Node Metastases Can Be Stratified into Clinically Relevant Prognostic Categories Using Oncogenic BRAF, the …
J Ricarte-Filho, I Ganly, M Rivera, N Katabi, W Fu… - Thyroid, 2012 - liebertpub.com
Background: Papillary thyroid carcinoma (PTC) patients presenting with cervical lymph
nodes (LN) metastases (M) have a variable outcome. The objective of this study is to assess …
nodes (LN) metastases (M) have a variable outcome. The objective of this study is to assess …
Molecular profiling related to poor prognosis in thyroid carcinoma. Combining gene expression data and biological information
C Montero-Conde, JM Martin-Campos, E Lerma… - Oncogene, 2008 - nature.com
Undifferentiated and poorly differentiated thyroid tumors are responsible for more than half
of thyroid cancer patient deaths in spite of their low incidence. Conventional treatments do …
of thyroid cancer patient deaths in spite of their low incidence. Conventional treatments do …