Traumatic brain injury (TBI) represents a major public health problem, which is associated
with neurological dysfunction. In severe or moderate cases of TBI, in addition to its high …

The present study evaluated the effectiveness of micronized palmitoylethanolamide (PEA‐
m) treatment in reducing the painful symptoms experienced by diabetic patients with …

Background It has recently been demonstrated that palmitoylethanolamide (PEA), an
endogenous lipid amide belonging to the N-acylethanolamine family, exerts neuroprotection …

The available treatments for patients affected by Alzheimer's disease (AD) are not curative.
Numerous clinical trials have failed during the past decades. Therefore, scientists need to …

Emerging evidence indicates that astrogliosis is involved in the pathogenesis of
neurodegenerative disorders. Our previous findings suggested cannabinoids and Autacoid …

Fatty acid ethanolamides (FAEs), which include palmitoylethanolamide (PEA) and
oleoylethanolamide (OEA), are endogenous agonists of peroxisome proliferator-activated …

Background Peripheral neuropathy is a common complication of diabetes. The management
of the associated neuropathic pain remains difficult to treat. Objective This study explored …

Neurodegenerative diseases are characterized by neuroinflammation, neuronal depletion
and oxidative stress. They coincide with subtle chronic or flaring inflammation, sometimes …

A high-fat diet induces hypothalamic inflammation in rodents which, in turn, contributes to
the development of obesity by eliciting both insulin and leptin resistance. However, the …

Background Animal models of sciatic nerve injury are commonly used to study neuropathic
pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion …