Abstract Interleukin 1β (IL-1β) is critical for the in vivo survival, expansion and effector
function of IL-17–producing helper T (TH17) cells during autoimmune responses, including …

Cytokine dysregulation is a central driver of chronic inflammatory diseases such as multiple
sclerosis (MS). Here, we sought to determine the characteristic cellular and cytokine …

Mesenchymal stromal cells (MSCs) of the bone marrow (BM) play key roles in regulating
hematopoietic function. Yet, knowledge on the compositional and functional dynamics of this …

Macrophage inflammatory protein‐3α/CCL20 is a recently identified chemokine that binds to
CCR6 and acts as a chemoattractant for memory/differentiated T‐cells, B‐cells, and …

GPCR expression was intensively studied in bulk cDNA of leukocyte populations, but limited
data are available with respect to expression in individual cells. Here, we show a …

Objective Paraneoplastic neurologic disorders (PND) are autoimmune diseases associated
with cancer and ectopic expression of a neuronal antigen in a peripheral tumor. Patients …

Research into multiple sclerosis (MS) has shown that cells purportedly important to myelin
repair within the CNS, namely neural stem cells (NSC) and oligodendrocyte progenitor cells …

CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites
and plays prominent roles in inflammatory pathologies and cancer. It has therefore been …

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation-
driven tissue fibrosis and vasculopathy. CXCL4 is a chemokine overexpressed in SSc and …

Background Monocyte subpopulations distinguished by differential expression of chemokine
receptors CCR2 and CX3CR1 are difficult to track in vivo, partly due to lack of CCR2 …