Background: Although renal tubular epithelium has a great capacity for repair it has been
suggested that the administration of mesenchymal stem cells may accelerate the recovery …

PURPOSE: The potential use of stem cells for acute and chronic renal injury is under
intensive investigation. We summarized the current literature on the potential therapeutic …

Adult stem cells have been characterized in several tissues as a subpopulation of cells able
to maintain, generate, and replace terminally differentiated cells in response to physiological …

The potential role of mesenchymal stem cells (MSCs, also called mesenchymal stromal
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …

Severe acute renal failure (ARF) remains a common, largely treatment-resistant clinical
problem with disturbingly high mortality rates. Therefore, we tested whether administration of …

Introduction Studies have shown that stem cells exert their therapeutic effects on acute
kidney injury (AKI) through paracrine/endocrine actions. If the protective effect is mediated in …

A current explanation for development of chronic renal injury is the imbalance between
injurious mechanism and regenerative repair. The possibility that stem cells contribute to the …

The most commonly used therapeutic targets in nephrology are the reduction of injury, the
delay of progression, or renal replacement therapy. Many animal and human studies …

The susceptibility of developing acute renal failure depends on the ability of the kidney to
recover from acute injury and regain normal function. Recently, the possible contribution of …

The recent findings indicate that under conditions of severe tubular injuries, transplantation
of mesenchymal stem cells (MSCs) may be a promising treatment in acute kidney diseases; …