I expressed Xenopus laevis cyclin A1 in the cellular slime mould Dictyostelium discoideum
to investigate the currently unclear role of A-type cyclins. Expression of this cyclin in the …

Cyclin B plays an essential role in cell cycle regulation by complexing with Cdc2 protein
kinase to direct cells into mitosis. A cyclin B gene (cycB) has been isolated from D …

Cyclins are highly conserved proteins that activate cyclin-dependent kinases (CDKs) to
regulate the cell cycle, transcription and other cellular processes. The completion of the …

ABSTRACT A cyclin gene has been isolated from Dictyostelium discoideum and the
available evidence indicates that the gene encodes a B type cyclin. The cyclin box region of …

Cyclins, as regulatory subunits of the ubiquitous p34cdc2 protein kinase, act as key
controlling elements of the eukaryotic cell cycle. We have examined published sequences of …

This thesis describes studies on cyclin A, a member of a family of proteins centrally involved
in the regulation of the eukaryotic cell cycle. Cyclins are activating subunits of the cdc2 …

Cyclin B plays an essential role in cell cycle regulation by complexing with Cdc2 protein
kinase to direct cells into mitosis. A cyclin B gene (cycB) has been isolated from D …

Cyclin-dependent kinases (Cdk) are a family of serine/threonine protein kinases that
regulate eukaryotic cell cycle progression. Their ability to modulate the cell cycle has made …

Although Dictyostelium differentiation occurs in the absence of external nutrients, two
periods of mitosis occur, one during early development and one during the formation of the …

Two new B‐type cyclin genes from Saccharomyces cerevisiae, called CLB5 and CLB6, are
located in a tail to tail arrangement adjacent to the G2/M phase promoting cyclins CLB2 and …