Spatial navigation and memory: A review of the similarities and differences relevant to brain models and age

AD Ekstrom, PF Hill - Neuron, 2023 - cell.com
Spatial navigation and memory are often seen as heavily intertwined at the cognitive and
neural levels of analysis. We review models that hypothesize a central role for the medial …

Close but no cigar: Spatial precision deficits following medial temporal lobe lesions provide novel insight into theoretical models of navigation and memory

BS Kolarik, T Baer, K Shahlaie, AP Yonelinas… - …, 2018 - Wiley Online Library
Increasing evidence suggests that the human hippocampus contributes to a range of
different behaviors, including episodic memory, language, short‐term memory, and …

Interacting networks of brain regions underlie human spatial navigation: a review and novel synthesis of the literature

AD Ekstrom, DJ Huffman… - Journal of …, 2017 - journals.physiology.org
Navigation is an inherently dynamic and multimodal process, making isolation of the unique
cognitive components underlying it challenging. The assumptions of much of the literature …

Extrahippocampal contributions to age differences in human spatial navigation

SD Moffat, KM Kennedy, KM Rodrigue, N Raz - Cerebral cortex, 2007 - academic.oup.com
The hippocampus (HC) and associated neural structures are hypothesized to contribute to
individual differences in human spatial navigation. However, functional imaging studies and …

The role of the hippocampus in navigation is memory

H Eichenbaum - Journal of neurophysiology, 2017 - journals.physiology.org
There is considerable research on the neurobiological mechanisms within the hippocampal
system that support spatial navigation. In this article I review the literature on navigational …

Segregating cognitive functions within hippocampal formation: A quantitative meta‐analysis on spatial navigation and episodic memory

S Kühn, J Gallinat - Human Brain Mapping, 2014 - Wiley Online Library
The most important cognitive domains where hippocampal formation is crucially involved
are navigation and memory. Some evidence suggests that different hippocampal subregions …

The aging navigational system

AW Lester, SD Moffat, JM Wiener, CA Barnes… - Neuron, 2017 - cell.com
The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …

The hippocampus and entorhinal cortex encode the path and Euclidean distances to goals during navigation

LR Howard, AH Javadi, Y Yu, RD Mill, LC Morrison… - Current Biology, 2014 - cell.com
Background Despite decades of research on spatial memory, we know surprisingly little
about how the brain guides navigation to goals. While some models argue that vectors are …

Extrahippocampal contributions to age-related changes in spatial navigation ability

JY Zhong, SD Moffat - Frontiers in Human Neuroscience, 2018 - frontiersin.org
Age-related decline in spatial navigation is well-known and the extant literature emphasizes
the important contributions of a hippocampus-dependent spatial navigation system in …

The complex nature of hippocampal-striatal interactions in spatial navigation

SC Goodroe, J Starnes, TI Brown - Frontiers in human neuroscience, 2018 - frontiersin.org
Decades of research have established the importance of the hippocampus for episodic and
spatial memory. In spatial navigation tasks, the role of the hippocampus has been classically …