Background The extracellular signal-regulated kinase (ERK) signaling pathway is
considered to be associated with the pathogenesis and treatment of depression …

Extracellular signal‐regulated kinase (ERK)‐cAMP response element binding protein
(CREB) signal pathway has been implicated in the pathogenesis of depression. There is …

Acupuncture has demonstrated the function in ameliorating depressive‐like behaviors via
modulating PKA/CREB signaling pathway. To further confirm the antidepressant mechanism …

Recently, emerging evidence has identified that stress-induced activation of
neuroinflammation is considered to be one of the most prevalently precipitating factors in the …

Oxidative stress is closely related to the occurrence of depression. Acupuncture has been
proved to be an effective method for treating depression. In order to explore the mechanism …

Depression is a serious psychiatric disorder with an enormous socioeconomic burden, and it
is commonly comorbid with pain, chronic fatigue, or other inflammatory diseases. Recent …

Protein kinase A (PKA)/cAMP response element‐binding (CREB) protein signaling pathway,
contributing to impaired neurogenesis parallel to depressive‐like behaviors, has been …

Background Acupuncture has shown the preventive effects on depression in rats with
chronic unpredictable mild stress (CUMS). However, the mechanisms of acupuncture for …

We investigate the antidepressant‐like effect and mechanism of electroacupuncture (EA) on
a chronic unpredictable mild stress rats depression‐like behavior. In our study, depression …

Objective. Depression is a global mental health problem with high disability rate, which
brings a huge disease burden to the world. Electroacupuncture (EA) has been shown to be …