Autophagy is an important mechanosensitive response for cellular homeostasis and survival
in osteocytes. However, the mechanism and its effect on bone metabolism have not yet …

Both mechanical loading and intracellular autophagy play important roles in bone
homeostasis; however, their relationship remains largely unexplored. The objectives of this …

Osteocytes sense extracellular mechanical stimuli and transduce them into biochemical
signals to regulate bone remodeling. The function is also evidenced in orthodontic tooth …

Bone homeostasis involves bone formation and bone resorption, which are processes that
maintain skeletal health. Oxidative stress is an independent risk factor, causing the …

Autophagy has been indicated to be involved in regulating bone metabolism. However, little
is known about the role of autophagy in mechanical stimulation-influenced osteoblast …

Autophagy is an evolutionarily conserved dynamic process and present in variety of cells at
basal levels to maintain homeostasis and to promote cell survival in response to stresses …

Autophagy is an evolutionary conserved and highly regulated recycling process of cellular
wastes. Having a housekeeping role, autophagy through the digestion of domestic cytosolic …

Autophagy may be a major mechanism by which osteoblasts (OBs) protect against the
negative effects of chronic glucocorticoid (GC) usage. OBs are closely associated with the …

Diabetes is a chronic disease that disrupts the balance between bone formation and bone
desorption, which can lead to osteoporosis, increasing the risk of fracture. However …

Bone remodeling is a tightly controlled mechanism in which osteoblasts (OB), the cells
responsible for bone formation, osteoclasts (OC), the cells specialized for bone resorption …