Modular synthesis of biodegradable diblock copolymers for designing functional polymersomes

JS Katz, S Zhong, BG Ricart, DJ Pochan… - Journal of the …, 2010 - ACS Publications
Polymer vesicles, or polymersomes, are promising candidates for applications in drug
delivery and tissue imaging. While a vast variety of polymers have been explored for their …

Detergent-aided polymersome preparation

HR Marsden, CB Quer, EY Sanchez… - …, 2010 - ACS Publications
Until now, most preparative methods used to form polymeric vesicles involve either organic
cosolvents or sonication. In this communication, we demonstrate for the first time a detergent …

Synthesis and characterization of reactive PEO–PMCL polymersomes

MA Petersen, L Yin, E Kokkoli, MA Hillmyer - Polymer Chemistry, 2010 - pubs.rsc.org
Targeted drug delivery offers the possibility to greatly improve treatment outcomes for
diseases such as cancer by enhancing specificity, thus minimizing detrimental side effects …

Microfluidic fabrication of monodisperse biocompatible and biodegradable polymersomes with controlled permeability

HC Shum, JW Kim, DA Weitz - Journal of the American Chemical …, 2008 - ACS Publications
We describe a versatile technique for fabricating monodisperse polymersomes with
biocompatible and biodegradable diblock copolymers for efficient encapsulation of actives …

Biodegradable polymersomes

F Meng, C Hiemstra, GHM Engbers, J Feijen - Macromolecules, 2003 - ACS Publications
Polymersomes, ie, polymer vesicles, have received great interest in recent years. It has been
shown that polymersomes can be formed from block copolymers using organic solvents, 1 …

Polymersomes for drug delivery and other biomedical applications

I Meerovich, AK Dash - Materials for biomedical engineering, 2019 - Elsevier
Polymersomes are self-assembled polymeric vesicles prepared from amphiphilic block-
copolymers. This chapter provides an overview of their composition, preparation, and …

Functionalized polymersomes for biomedical applications

PV Pawar, SV Gohil, JP Jain, N Kumar - Polymer Chemistry, 2013 - pubs.rsc.org
Polymersomes are latest entry to the drug carrier systems and have proven their utility to
deliver therapeutic agents to specific tissues/organs due to their versatile polymeric …

Polymersomes: a new multi-functional tool for cancer diagnosis and therapy

DH Levine, PP Ghoroghchian, J Freudenberg, G Zhang… - Methods, 2008 - Elsevier
Nanoparticles are being developed as delivery vehicles for therapeutic pharmaceuticals and
contrast imaging agents. Polymersomes (mesoscopic polymer vesicles) possess a number …

Recent advances in formation, properties, and applications of polymersomes

JF Liao, C Wang, YJ Wang, F Luo… - Current pharmaceutical …, 2012 - ingentaconnect.com
Polymersomes are self-assembled spherical vesicles based on amphiphilic block
copolymers. This review presents a summary of the achievements in the field of …

A novel method for the encapsulation of biomolecules into polymersomes via direct hydration

CP O'Neil, T Suzuki, D Demurtas, A Finka, JA Hubbell - Langmuir, 2009 - ACS Publications
One of the major engineering challenges for the implementation of block copolymer
vesicles, or polymersomes, as therapeutic drug carriers is obtaining high encapsulation …