Cancer stem cells (CSCs) are responsible for tumor initiation and progression. We
previously showed that Delta-like homolog 1 (DLK1) may be a therapeutic target against the …

Abstract Delta-like 1 homolog (DLK1; Drosophila) is a hepatic stem/progenitor cell marker in
fetal livers that plays a vital role in oncogenesis of hepatocellular carcinoma (HCC). The aim …

Abstract Background: Delta‐like 1 (DLK1), a fetal liver stem cell marker, is strongly
expressed in human and rodent fetal liver, but not in adult liver. Notably, dysregulation of …

Abstract DEAD box RNA helicase 17 (DDX17) is a transcriptional regulator of several
transcription factors, which is more appreciated than its role in RNA metabolism. However …

Tetraspanins CD9 and CD81 frequently serve as the surface markers of exosomes, which
are involved in intercellular communication during tumor progression. KLF4 is a well-known …

Tumor stem cell marker Doublecortin-like kinase1 (DCLK1) is upregulated in several solid
tumors. The role of DCLK1 in hepatocellular carcinoma (HCC) is unclear. We …

Background Hepatocellular carcinoma (HCC) remains difficult to cure due to lack of effective
treatment and the molecular mechanisms are complex and not completely understood. In …

Recent research has shown that Doublecortin-like kinase 1 (DCLK1) is overexpressed in
different types of cancer. It has recently been described as a cancer stem cells (CSCs) …

Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and the third most
frequent cause of cancer-related death in developing countries, especially in East Asia and …

To investigate the clinical role and biological function of cyclin-dependent kinase 5 (CDK5)
in hepatocellular carcinoma (HCC), 412 surgically resected tissue samples (HCC, n= 171; …