Toll-Like Receptor 4 (TLR4) is one of the receptors of innate immunity. It is activated by
Pathogen-and Damage-Associated Molecular Patterns (PAMPs and DAMPs) and triggers …

Endosomal Toll-like receptors (TLR3, TLR7, TLR8, and TLR9) are highly analogous sensors
for various viral or bacterial RNA and DNA molecular patterns. Nonetheless, few small …

Abstract Background Toll-like receptors (TLRs) are an important family of receptors that
constitute the first line of defense system against microbes. They can recognize both …

The health of living organisms is constantly challenged by bacterial and viral threats. The
recognition of pathogenic microorganisms by diverse receptors triggers a variety of host …

ABSTRACT Introduction: Pattern recognition receptors (PRRs) of the innate immune system
mediate and control the activation and progression of adaptive immunity. Toll-like receptors …

Roles for Toll-like receptors (TLRs) are emerging in conditions such as sepsis syndrome,
systemic lupus erythromatosis, rheumatoid arthritis and asthma, suggesting that the …

Toll-like receptors (TLRs) are a family of proteins playing important roles in host defense.
Mice defective of functional TLR4 are hyporesponsive to LPS, suggesting that TLR4 is …

Toll‐like receptor 4 (TLR4) belongs to the family of pattern recognition receptors (PRRs).
They are highly conserved receptors that recognize conserved pathogen‐associated …

There is a growing interest in the targeting of Toll-like receptors (TLRs) for the prevention
and treatment of cancer, rheumatoid arthritis, inflammatory bowel disease and systemic …

Abstract Sepsis remains the most common cause of death in intensive care units in the USA,
with a current estimate of at least 750,000 cases per year, and 215,000 deaths annually …