Uropathogenic Escherichia coli (UPEC) is a major pathogen that causes urinary tract
infection (UTI). This bacterium adheres to and internalizes within urinary tract cells, where it …

Type 1 pilus directs bladder epithelial binding and invasion by uropathogenic Escherichia
coli (UPEC) in the initial stage of cystitis, but the bacterial determinants of postinvasion …

Urinary tract infection (UTI) is one of the most common bacterial infections in humans, with
uropathogenic Escherichia coli (UPEC) the leading causative organism. UPEC has a …

Uropathogenic Escherichia coli (UPEC) is a major causative agent of urinary tract infections.
The bacteria internalize into the uroepithelial cells, where aggregate and form …

OmpT is one of the members of the outer membrane protein family that has been identified
as a virulence factor in most of the uropathogenic Escherichia coli (UPEC). However, the …

The phoU gene is the last cistron in the pstSCAB–phoU operon and functions as a negative
regulator of the Pho regulon. The authors previously identified a phoU mutant of …

In the murine model of urinary tract infections (UTI), cystitis by uropathogenic Escherichia
coli (UPEC) occurs through an intimate relationship with the bladder superficial umbrella cell …

Background Type II secretion systems (T2SS) and the evolutionarily related type IV pili (T4P)
are important virulence determinants in many Gram-negative bacterial pathogens. However …

Urinary tract infections primarily caused by uropathogenic strains of Escherichia coli (E. coli)
remain a significant public health problem in both developed and developing countries. An …

The pstSCAB-phoU operon encodes the phosphate-specific transport system (Pst). Loss of
Pst constitutively activates the Pho regulon and decreases bacterial virulence. However …