BACKGROUND: The protective effects of 17-beta estradiol (E2) on cardiac tissue during
ischemia/reperfusion (I/R) injury have not yet been fully elucidated. OBJECTIVE: To assess …

Aims The aims of this study were to determine whether chronic oestrogen withdrawal
influences the development of ischaemic preconditioning (IPC) in female hearts, to …

Although several studies have demonstrated that chronic exposure to estrogen appears to
be cardioprotective, acute circulatory effects of estrogen are largely unknown. Therefore, we …

To study the cell signaling events leading to 17β-estradiol (E2)-induced acute
cardioprotection, we subjected isolated rat hearts to three 5-min cycles of 10 μM E2 before …

Murry et al.[1], devised the promising technique of preconditioning to salvage the
myocardium from perfusion's subsequent ischemic insult. This technique is used for …

The role of physiologic estrogen levels (pg) on post-ischemic myocardial function was
studied in the isolated working rat heart without (n= 28, experiment No. 1) or with (n= 15 …

BACKGROUND: Females demonstrate improved cardiac recovery after
ischemia/reperfusion injury compared with males. Attenuation of myocardial dysfunction with …

Aim: Ischaemic preconditioning (IPC) has been demonstrated to protect heart function and
viability, but has been predominantly studied in male animals. Methods: We studied a …

Background Brief myocardial ischemia is associated with myocardial and coronary
endothelial dysfunction caused by oxygen free radicals released during reperfusion …

Cardiac tissue that undergoes an ischemic episode exhibits irreversible alterations that
become more extensive upon reperfusion. Estrogen treatment has been reported to protect …