Antioxidant response element (ARE) regulates the induction of a number of cellular
antioxidant and detoxifying enzymes. However, the signaling pathways that lead to ARE …

A coordinated cellular response to oxidative stress occurs in part through transcriptional
regulation via a cis-acting sequence known as the antioxidant response element (ARE). NF …

Nrf2, a basic leucine zipper transcription factor, is an essential activator of the coordinated
transcription of genes encoding antioxidant enzymes and phase II detoxifying enzymes …

Transcription factor Nrf2 is essential for the antioxidant responsive element (ARE)-mediated
induction of phase II detoxifying and oxidative stress enzyme genes. Detailed analysis of …

Nrf1 is a member of the vertebrate Cap'n'Collar (CNC) transcription factor family that
commonly contains a unique basic-leucine zipper domain. Among CNC family members …

Eukaryotic cells counteract oxidative and other environmental stress through the activation
of Nrf2, the transcription factor that controls the expression of a host of protective enzymes by …

Antioxidant response element (ARE)-mediated expression and coordinated induction of
antioxidant enzymes is a critical mechanism of protection against chemically induced …

The antioxidant responsive element (ARE) is a cis-acting regulatory element of genes
encoding phase II detoxification enzymes and antioxidant proteins, such as NAD (P) H …

Exposure to antioxidants and xenobiotics triggers the expression of a myriad of genes
encoding antioxidant proteins, detoxifying enzymes, and xenobiotic transporters to offer …

Antioxidant response element (ARE)-mediated expression and coordinated induction of
genes encoding detoxifying enzymes is one mechanism of critical importance to cellular …