Abstract In the United Kingdom (UK), it is projected that by 2035 people aged> 65 years will
make up 23% of the population, with those aged> 85 years accounting for 5% of the total …

Worldwide estimates predict 2 billion people will be aged over 65 years by 2050. A major
current challenge is maintaining mobility and quality of life into old age. Impaired mobility is …

A substantial loss of muscle mass and strength (sarcopenia), a decreased regenerative
capacity, and a compromised physical performance are hallmarks of aging skeletal muscle …

Skeletal muscles comprise a substantial portion of whole body mass and are integral for
locomotion and metabolic health. Increasing age is associated with declines in both muscle …

The longitudinal changes in isokinetic strength of knee and elbow extensors and flexors,
muscle mass, physical activity, and health were examined in 120 subjects initially 46 to 78 …

Aging is usually accompanied by a significant reduction in muscle mass and force. To
determine the relative contribution of inactivity and aging per se to this decay, we compared …

Skeletal muscle is a highly plastic tissue that remarkably adapts to diverse stimuli including
exercise, injury, disuse, and, as discussed here, aging. Humans achieve peak skeletal …

Skeletal muscle is integral to the metabolism and utilisation of macronutrients; however,
substantial muscle loss and morphological changes occur with ageing. These are …

The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

Age-related loss of skeletal muscle mass and function, sarcopenia, is associated with
physical frailty and increased risk of morbidity (chronic diseases), in addition to all-cause …