[PDF][PDF] Treatment strategies in cervical cancer: treatment of advanced disease

A Valdivia, JF Grau-Béjar, C García-Durán… - J Cancer Metastasis …, 2022 - f.oaes.cc
Cervical cancer is the fourth most common cancer in women worldwide, with a global
incidence of 604,127 and an annual death rate of 341,831 in 2020. Patients with recurrent …

Current treatment for cervical cancer: an update

S Sharma, A Deep, AK Sharma - Anti-Cancer Agents in …, 2020 - ingentaconnect.com
Cervical cancer is the leading gynecologic health problem which is considered as the 4th
most widespread tumour in women. The prevalence of this fatal ailment is emerging …

Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic …

KS Tewari, MW Sill, RT Penson, H Huang… - The Lancet, 2017 - thelancet.com
Summary Background On Aug 14, 2014, the US Food and Drug Administration approved the
antiangiogenesis drug bevacizumab for women with advanced cervical cancer on the basis …

Improved survival with bevacizumab in advanced cervical cancer

KS Tewari, MW Sill, HJ Long III… - … England Journal of …, 2014 - Mass Medical Soc
Background Vascular endothelial growth factor (VEGF) promotes angiogenesis, a mediator
of disease progression in cervical cancer. Bevacizumab, a humanized anti-VEGF …

Breaking down the evidence for bevacizumab in advanced cervical cancer: past, present and future

V Rodriguez-Freixinos, HJ Mackay - Gynecologic oncology research and …, 2015 - Springer
Despite the introduction of screening and, latterly, vaccination programs in the developed
world, globally cervical cancer remains a significant health problem. For those diagnosed …

Paclitaxel-carboplatin and bevacizumab combination with maintenance bevacizumab therapy for metastatic, recurrent, and persistent uterine cervical cancer: an open …

T Tanigawa, N Takeshima, H Ishikawa, S Nishio… - Gynecologic …, 2022 - Elsevier
Objective This multicenter, open-label, phase II study aimed to evaluate the efficacy and
safety of paclitaxel–carboplatin, bevacizumab, and bevacizumab-based maintenance …

Targeted treatments for cervical cancer: a review

O Peralta-Zaragoza, VH Bermúdez-Morales… - OncoTargets and …, 2012 - Taylor & Francis
Cervical cancer is the second most common cause of cancer death in women worldwide
and the development of new diagnosis, prognostic, and treatment strategies merits special …

Twenty-first century cervical cancer management: a historical perspective of the gynecologic oncology group/NRG oncology over the past twenty years

CA Leath III, BJ Monk - Gynecologic oncology, 2018 - Elsevier
Abstract Since 1970, the Gynecologic Oncology Group (GOG) has been at the forefront of
evaluating and helping to implement ground breaking and paradigm changing research in …

Chemotherapy for advanced, recurrent, and metastatic cervical cancer

DH Moore - Journal of the National Comprehensive Cancer …, 2008 - jnccn.org
When cervical cancer is beyond curative treatment with surgery or radiation therapy, the
prognosis is poor and palliation is the primary objective. Early prospective studies identified …

Primary results from CECILIA, a global single-arm phase II study evaluating bevacizumab, carboplatin and paclitaxel for advanced cervical cancer

A Redondo, N Colombo, M McCormack, L Dreosti… - Gynecologic …, 2020 - Elsevier
Objective Adding bevacizumab to cisplatin–paclitaxel for advanced cervical cancer
significantly improves overall and progression-free survival. We evaluated bevacizumab …